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Orai3 Gene Detail
Summary
  • Symbol
    Orai3
  • Name
    ORAI calcium release-activated calcium modulator 3
  • Synonyms
    Tmem142c
  • Feature Type
    protein coding gene
  • IDs
    MGI:3039586
    NCBI Gene: 269999
Location & Maps
more
  • Sequence Map
    Chr7:127769815-127775150 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5336 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 69.73 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ORAI3, ORAI calcium release-activated calcium modulator 3
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ORAI3, ORAI calcium release-activated calcium modulator 3
    Orthology source: HomoloGene
  • Synonyms
    TMEM142C
  • Links
    NCBI Gene ID: 93129
    neXtProt AC: NX_Q9BRQ5

  • Chr Location
    16p11.2; chr16:30949084-30954938 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    16
  • Gene trapped
    15
  • Targeted
    1
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031096 VEGA Gene Model | MGI Sequence Detail 5336 C57BL/6J ±  kb
transcript OTTMUST00000077039 VEGA | MGI Sequence Detail 1996 Not Applicable  
polypeptide OTTMUSP00000040631 VEGA | MGI Sequence Detail 290 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    7 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000012028 protein orai-3
  • InterPro Domains
    IPR012446 Calcium release-activated calcium channel protein
    IPR030032 Protein Orai-3
Molecular
Reagents
less
  • All nucleic 31
    cDNA 31

    Microarray probesets 1
References
more
  • Summaries
    All 24
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory