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Dclk3 Gene Detail
Summary
  • Symbol
    Dclk3
  • Name
    doublecortin-like kinase 3
  • Synonyms
    Click-I, -II related, Dcamkl3
  • Feature Type
    protein coding gene
  • IDs
    MGI:3039580
    NCBI Gene: 245038
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:111439081-111489118 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 61.33 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    529 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3039580
protein coding gene Chr9:111439081-111489611 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035374
protein coding gene Chr9:113679876-113730629 (+)
A/J MGP_AJ_G0035355
protein coding gene Chr9:109513962-109563964 (+)
AKR/J MGP_AKRJ_G0035286
protein coding gene Chr9:112245753-112298741 (+)
BALB/cJ MGP_BALBcJ_G0035350
protein coding gene Chr9:109264509-109314831 (+)
C3H/HeJ MGP_C3HHeJ_G0035058
protein coding gene Chr9:112749083-112801242 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035872
protein coding gene Chr9:116786663-116839223 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032758
protein coding gene Chr9:106715690-106767296 (+)
CAST/EiJ MGP_CASTEiJ_G0034364
protein coding gene Chr9:112565293-112616770 (+)
CBA/J MGP_CBAJ_G0035025
protein coding gene Chr9:121105080-121160174 (+)
DBA/2J MGP_DBA2J_G0035184
protein coding gene Chr9:108961521-109014307 (+)
FVB/NJ MGP_FVBNJ_G0035131
protein coding gene Chr9:107802427-107854836 (+)
LP/J MGP_LPJ_G0035263
protein coding gene Chr9:113951711-114005771 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035171
protein coding gene Chr9:122402381-122457791 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035892
protein coding gene Chr9:112599727-112652042 (+)
PWK/PhJ MGP_PWKPhJ_G0034071
protein coding gene Chr9:109222168-109276312 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033906
protein coding gene Chr9:112698387-112754506 (+)
WSB/EiJ MGP_WSBEiJ_G0034485
protein coding gene Chr9:112458509-112520343 (+)



Homology
more
  • Human Ortholog
    DCLK3, doublecortin like kinase 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    DCLK3, doublecortin like kinase 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CLR, DCAMKL3, DCDC3C, DCK3
  • Links
    NCBI Gene ID: 85443
    neXtProt AC: NX_Q9C098
    UniProt: Q9C098

  • Chr Location
    3p22.2; chr3:36712422-36764206 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032500 Ensembl Gene Model | MGI Sequence Detail 50038 C57BL/6J ±  kb
transcript ENSMUST00000111879 Ensembl | MGI Sequence Detail 3005 Not Applicable  
polypeptide ENSMUSP00000107510 Ensembl | MGI Sequence Detail 790 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 3
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:263425 Galvan L, et al., The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin. Brain. 2018 May 1;141(5):1434-1454

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory