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Dclk3 Gene Detail
Summary
  • Symbol
    Dclk3
  • Name
    doublecortin-like kinase 3
  • Synonyms
    Click-I, -II related, Dcamkl3
  • Feature Type
    protein coding gene
  • IDs
    MGI:3039580
    NCBI Gene: 245038
Location & Maps
more
  • Sequence Map
    Chr9:111439081-111489118 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      50038 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 61.33 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    DCLK3, doublecortin like kinase 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    DCLK3, doublecortin like kinase 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CLR, DCAMKL3, DCDC3C, DCK3
  • Links
    NCBI Gene ID: 85443
    neXtProt AC: NX_Q9C098

  • Chr Location
    3p22.2; chr3:36712422-36764204 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027483 VEGA Gene Model | MGI Sequence Detail 50038 C57BL/6J ±  kb
transcript OTTMUST00000068016 VEGA | MGI Sequence Detail 3005 Not Applicable  
polypeptide OTTMUSP00000034308 VEGA | MGI Sequence Detail 790 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    529 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000006312 serine/threonine-protein kinase DCLK3
  • EC
  • InterPro Domains
    IPR020636 Calcium/calmodulin-dependent/calcium-dependent protein kinase
    IPR003533 Doublecortin domain
    IPR017441 Protein kinase, ATP binding site
    IPR000719 Protein kinase domain
    IPR011009 Protein kinase-like domain
    IPR008271 Serine/threonine-protein kinase, active site
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:219340 Molyneaux BJ, et al., DeCoN: genome-wide analysis of in vivo transcriptional dynamics during pyramidal neuron fate selection in neocortex. Neuron. 2015 Jan 21;85(2):275-88

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory