Mmp27
Gene Detail

Symbol Name ID

Mmp27 matrix metallopeptidase 27 MGI:3039232

Synonyms

LOC234911

Feature Type

protein coding gene

Genetic Map

Chromosome 9

2.46 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr9:7571396-7581885 bp, + strand From VEGA annotation of GRCm38   10490 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:23345  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: matrix metalloproteinase, stromelysin type
Gene Tree: Mmp27

Human homologs

Human Homolog		MMP27, matrix metallopeptidase 27
NCBI Gene ID		64066
neXtProt AC		NX_Q9H306
Human Synonyms		MMP-27
Human Chr (Location)		11q24; chr11:102562415-102576468 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	proteolysis
Component	cellular_component
Function	hydrolase activity, metal ion binding, ...

External Resources: FuncBase

Expression

cDNA source data(3)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(4) cDNA(3) Other(1)
Microarray probesets(1)

Other database links

VEGA Gene Model	OTTMUSG00000031478 (Evidence)
Ensembl Gene Model	ENSMUSG00000070323 (Evidence)
Entrez Gene	234911 (Evidence)
UniGene	334940
DoTS	DT.101302082, DT.110627970
NIA Mouse Gene Index	U192456
Consensus CDS Project	CCDS40530.1
International Mouse Knockout Project Status	Mmp27

Sequences

Length	Strain/Species
genomic	OTTMUSG00000031478	VEGA Gene Model | MGI Sequence Detail	10490	C57BL/6J
transcript	OTTMUST00000077986	VEGA | MGI Sequence Detail	1654	Not Applicable
polypeptide	OTTMUSP00000041377	VEGA | MGI Sequence Detail	551	Not Applicable

All sequences(28) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(45 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000585	Hemopexin/matrixin
InterPro	IPR018486	Hemopexin/matrixin, conserved site
InterPro	IPR018487	Hemopexin/matrixin, repeat
InterPro	IPR024079	Metallopeptidase, catalytic domain
InterPro	IPR021158	Peptidase M10A, cysteine switch, zinc binding site
InterPro	IPR021190	Peptidase M10A, matrix metallopeptidase
InterPro	IPR016293	Peptidase M10A, matrix metallopeptidase, stromelysin type
InterPro	IPR001818	Peptidase M10, metallopeptidase
InterPro	IPR006026	Peptidase, metallopeptidase
InterPro	IPR002477	Peptidoglycan binding-like
Protein Ontology	PR:000010486	matrix metalloproteinase-27

References

(Earliest) J:89162 Nuttall RK, et al., Expression analysis of the entire MMP and TIMP gene families during mouse tissue development. FEBS Lett. 2004 Apr 9;563(1-3):129-34
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(24)

Other accession IDs

MGI:2685026