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H2afy2 Gene Detail
Summary
  • Symbol
    H2afy2
  • Name
    H2A histone family, member Y2
  • Synonyms
    macroH2A2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3037658
    NCBI Gene: 404634
  • Gene Overview
    MyGene.info: H2AFY2
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:61738640-61784103 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 32.27 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    151 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3037658
protein coding gene Chr10:61738640-61784147 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017288
protein coding gene Chr10:61107551-61155438 (-)
A/J MGP_AJ_G0017266
protein coding gene Chr10:59267781-59314817 (-)
AKR/J MGP_AKRJ_G0017226
protein coding gene Chr10:60813871-60861136 (-)
BALB/cJ MGP_BALBcJ_G0017226
protein coding gene Chr10:59344457-59389612 (-)
C3H/HeJ MGP_C3HHeJ_G0017049
protein coding gene Chr10:60717886-60765693 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017684
protein coding gene Chr10:63307372-63356124 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015375
protein coding gene Chr10:56242159-56288659 (-)
CAST/EiJ MGP_CASTEiJ_G0016620
protein coding gene Chr10:60735143-60836227 (-)
CBA/J MGP_CBAJ_G0017021
protein coding gene Chr10:65650329-65710627 (-)
DBA/2J MGP_DBA2J_G0017126
protein coding gene Chr10:58538708-58584520 (-)
FVB/NJ MGP_FVBNJ_G0017120
protein coding gene Chr10:57790961-57837895 (-)
LP/J MGP_LPJ_G0017201
protein coding gene Chr10:61499733-61551522 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017148
protein coding gene Chr10:67953272-67999560 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017722
protein coding gene Chr10:60640981-60690712 (-)
PWK/PhJ MGP_PWKPhJ_G0016403
protein coding gene Chr10:58390853-58438482 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016186
protein coding gene Chr10:60007908-60053836 (-)
WSB/EiJ MGP_WSBEiJ_G0016684
protein coding gene Chr10:60553790-60600233 (-)



Homology
more
  • Human Ortholog
    H2AFY2, H2A histone family member Y2
  • Vertebrate Orthologs
    11
  • Human Ortholog
    H2AFY2, H2A histone family member Y2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    macroH2A2
  • Links
    NCBI Gene ID: 55506
    neXtProt AC: NX_Q9P0M6
    UniProt: Q9P0M6

  • Chr Location
    10q22.1; chr10:70052601-70112284 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 10246
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: H2AFY2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotypes from multigenic genotypes
    12 phenotype references
Mice homozygous for a knock-out allele do not exhibit any developmental or reproductive abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 404634 NCBI Gene Model | MGI Sequence Detail 45464 C57BL/6J ±  kb
transcript NM_207000 RefSeq | MGI Sequence Detail 1910 C57BL/6  
polypeptide Q8CCK0 UniProt | EBI | MGI Sequence Detail 372 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 78
    cDNA 78

    Microarray probesets 7
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 12
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:260739 Haque N, et al., ZFR coordinates crosstalk between RNA decay and transcription in innate immunity. Nat Commun. 2018 Mar 20;9(1):1145

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory