Zfp532 MGI Mouse Gene Detail - MGI:3036282

Symbol

Zfp532
Name

zinc finger protein 532
Synonyms

C530030I18Rik

Feature Type

protein coding gene
IDs

MGI:3036282
NCBI Gene: 328977
Alliance

gene page
Transcription Start Sites

16 TSS

Sequence Map

Chr18:65713301-65822514 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 18, 38.91 cM
Mapping Data

1 experiment

SNPs within 2kb

3037 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3036282	protein coding gene	Chr18:65712983-65822514 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0024509	protein coding gene	Chr18:65727727-65845208 (+)
A/J	MGP_AJ_G0024476	protein coding gene	Chr18:62872047-62982842 (+)
AKR/J	MGP_AKRJ_G0024446	protein coding gene	Chr18:64651666-64765351 (+)
BALB/cJ	MGP_BALBcJ_G0024475	protein coding gene	Chr18:63013177-63124579 (+)
C3H/HeJ	MGP_C3HHeJ_G0024243	protein coding gene	Chr18:64854580-64967760 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0024922	protein coding gene	Chr18:67472256-67587890 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0022353	protein coding gene	Chr18:62316777-62426657 (+)
CAST/EiJ	MGP_CASTEiJ_G0023716	protein coding gene	Chr18:64842362-64958507 (+)
CBA/J	MGP_CBAJ_G0024213	protein coding gene	Chr18:69715305-69832212 (+)
DBA/2J	MGP_DBA2J_G0024343	protein coding gene	Chr18:62542713-62653293 (+)
FVB/NJ	MGP_FVBNJ_G0024309	protein coding gene	Chr18:61923754-62032786 (+)
LP/J	MGP_LPJ_G0024427	protein coding gene	Chr18:65583716-65701652 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0024338	protein coding gene	Chr18:71119220-71236055 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0024969	protein coding gene	Chr18:64861890-64972106 (+)
PWK/PhJ	MGP_PWKPhJ_G0023459	protein coding gene	Chr18:62786868-62898059 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0023264	protein coding gene	Chr18:65013914-65125005 (+)
WSB/EiJ	MGP_WSBEiJ_G0023780	protein coding gene	Chr18:64719700-64837363 (+)

Human Ortholog

ZNF532, zinc finger protein 532

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ZNF532, zinc finger protein 532
Links

HGNC:30940

NCBI Gene ID: 55205

UniProt: Q9HCE3
Chr Location

18q21.32; chr18:58862600-58986480 (+) GRCh38

MGI Vertebrate Homology

Zfp532 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: ZNF532
Gene Tree

Zfp532

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Phenotype Summary

9 phenotypes from 1 allele in 1 genetic background
10 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

504
Endonuclease-mediated

1
Gene trapped

501
Targeted

2
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

482 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

1
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

740
Tissues

33
cDNA Data

8
Literature Summary

3

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GENSAT

GEO

Expression Atlas

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All Sequences

108
RefSeq

8
UniProt

19
CCDS

CCDS29307.1, CCDS89265.1

Ensembl

ENSMUSG00000042439 (Evidence)
NCBI Gene

328977

			Length	Strain/Species	Flank
genomic	328977	NCBI Gene Model \| MGI Sequence Detail	109214	C57BL/6J	± kb
transcript	NM_001361053	RefSeq \| MGI Sequence Detail	6418	C57BL/6
polypeptide	Q6NXK2	UniProt \| EBI \| MGI Sequence Detail	1036	Not Applicable

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UniProt

19 Sequences
Protein Ontology

PR:000017961 zinc finger protein 532

(term hierarchy)
InterPro Domains

IPR036236 Zinc finger C2H2 superfamily

IPR013087 Zinc finger C2H2-type

IPR041697 Zinc-finger C2H2-type 11

IPR045914 Zinc finger protein 532-like
GlyGen

Q6NXK2 6 sites, 1 O-linked glycan (5 sites)

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All nucleic 8

cDNA 8

Microarray probesets 3

Summaries

All 30

Developmental Gene Expression 3

Gene Ontology 1

Phenotypes 10
Earliest

J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Zfp532:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr151678	Chr18:65713448-65713471 (+)	159 bp
Tssr151679	Chr18:65713827-65713869 (+)	547 bp
Tssr151680	Chr18:65713871-65713888 (+)	579 bp
Tssr151681	Chr18:65714775-65714832 (+)	1,503 bp
Tssr151682	Chr18:65715328-65715346 (+)	2,036 bp
Tssr151683	Chr18:65715352-65715381 (+)	2,066 bp
Tssr151684	Chr18:65715419-65715436 (+)	2,127 bp
Tssr151685	Chr18:65715461-65715470 (+)	2,165 bp
Tssr151686	Chr18:65716253-65716265 (+)	2,958 bp
Tssr151687	Chr18:65720533-65720547 (+)	7,239 bp
Tssr151688	Chr18:65720555-65720568 (+)	7,261 bp
Tssr151689	Chr18:65721182-65721199 (+)	7,890 bp
Tssr151690	Chr18:65727255-65727257 (+)	13,955 bp
Tssr151691	Chr18:65757104-65757142 (+)	43,822 bp
Tssr151692	Chr18:65759919-65759925 (+)	46,621 bp
Tssr151693	Chr18:65764814-65764818 (+)	51,515 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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