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Kcnt2
Gene Detail
Symbol

Name
ID
Kcnt2
potassium channel, subfamily T, member 2
MGI:3036273
Synonyms
E330038N15Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 1
61.62 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr1:140246158-140612067 bp, + strand
From VEGA annotation of GRCm38

  365910 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:16121  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: KCNT2
Gene Tree: Kcnt2

Human
homologs
KCNT2, potassium channel, sodium activated subfamily T, member 2
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 343450
neXtProt AC: NX_Q6UVM3

Human Synonyms: KCa4.2, SLICK, SLO2.1

Human Chr (Location): 1q31.3; chr1:196225779-196608560 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(26) : Gene trapped(24) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Kcnt2 interacts with 310 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
cDNA source data(1)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase kcnt2    NEW 
Molecular
reagents
All nucleic(1) cDNA(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000029830 (Evidence)
Ensembl Gene Model ENSMUSG00000052726 (Evidence)
Entrez Gene 240776 (Evidence)
DFCI TC1728973, TC1623498
DoTS DT.55227290, DT.91402377
NIA Mouse Gene Index U193455, U000886
Consensus CDS Project CCDS48389.1
International Mouse Phenotyping Consortium Status Kcnt2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029830 VEGA Gene Model | MGI Sequence Detail 365910 C57BL/6J ±  kb
transcript OTTMUST00000074239 VEGA | MGI Sequence Detail 3540 Not Applicable 
polypeptide OTTMUSP00000038560 VEGA | MGI Sequence Detail 1135 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(23) UniProt(5)
Polymorphisms
SNPs within 2kb(1638 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1642)
Protein-related
information
ResourceIDDescription
InterPro IPR013099 Ion transport 2
InterPro IPR016040 NAD(P)-binding domain
InterPro IPR003929 Potassium channel, calcium-activated, BK, alpha subunit
Protein Ontology PR:000002081 potassium channel subfamily T member 2
References
(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:198109 Oeschger FM, et al., Gene expression analysis of the embryonic subplate. Cereb Cortex. 2012 Jun;22(6):1343-59
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory