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Syde2 Gene Detail
Summary
  • Symbol
    Syde2
  • Name
    synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
  • Synonyms
    C430017H16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3036264
    NCBI Gene: 214804
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:145987870-146021720 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 71.03 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    252 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3036264
protein coding gene Chr3:145987354-146021720 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027965
protein coding gene Chr3:149444412-149493449 (+)
A/J MGP_AJ_G0027924
protein coding gene Chr3:144124309-144161009 (+)
AKR/J MGP_AKRJ_G0027890
protein coding gene Chr3:147964382-148001193 (+)
BALB/cJ MGP_BALBcJ_G0027936
protein coding gene Chr3:143940010-143975950 (+)
C3H/HeJ MGP_C3HHeJ_G0027666
protein coding gene Chr3:148326242-148362569 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028379
protein coding gene Chr3:154501400-154534921 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025717
protein coding gene Chr3:139198366-139231904 (+)
CAST/EiJ MGP_CASTEiJ_G0027119
protein coding gene Chr3:148296168-148303459 (+)
CBA/J MGP_CBAJ_G0027641
protein coding gene Chr3:159947660-159985511 (+)
DBA/2J MGP_DBA2J_G0027781
protein coding gene Chr3:143262913-143301517 (+)
FVB/NJ MGP_FVBNJ_G0027748
protein coding gene Chr3:140673277-140708862 (+)
LP/J MGP_LPJ_G0027892
protein coding gene Chr3:150843861-150881029 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027781
protein coding gene Chr3:168259156-168296997 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028438
protein coding gene Chr3:147549985-147587133 (+)
PWK/PhJ MGP_PWKPhJ_G0026842
protein coding gene Chr3:143110160-143145980 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026670
protein coding gene Chr3:145713113-145751953 (+)
WSB/EiJ MGP_WSBEiJ_G0027199
protein coding gene Chr3:148505613-148540557 (+)



Homology
more
  • Human Ortholog
    SYDE2, synapse defective Rho GTPase homolog 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SYDE2, synapse defective Rho GTPase homolog 2
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 84144
    neXtProt AC: NX_Q5VT97
    UniProt: Q5VT97

  • Chr Location
    1p22.3; chr1:85157673-85201725 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 19035
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SYDE2
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036863 Ensembl Gene Model | MGI Sequence Detail 33851 C57BL/6J ±  kb
transcript ENSMUST00000039517 Ensembl | MGI Sequence Detail 5495 Not Applicable  
polypeptide ENSMUSP00000041897 Ensembl | MGI Sequence Detail 1314 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR035892 C2 domain superfamily
    IPR000198 Rho GTPase-activating protein domain
    IPR008936 Rho GTPase activation protein
Molecular
Reagents
less
  • All nucleic 26
    cDNA 25
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 20
    Developmental Gene Expression 1
    Diseases 1
    Phenotypes 3
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:241798 Lo HF, et al., Association of dysfunctional synapse defective 1 (SYDE1) with restricted fetal growth - SYDE1 regulates placental cell migration and invasion. J Pathol. 2017 Feb;241(3):324-336

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/07/2019
MGI 6.14
The Jackson Laboratory