Dennd2c
Gene Detail

Symbol Name ID

Dennd2c DENN/MADD domain containing 2C MGI:3036254

Synonyms

A930010I20Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 3

45.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr3:103102604-103169769 bp, + strand From VEGA annotation of GRCm38   67166 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:19542  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Dennd2c

Human homologs

Human Homolog		DENND2C, DENN/MADD domain containing 2C
NCBI Gene ID		163259
neXtProt AC		NX_Q68D51
Human Synonyms		dJ1156J9.1
Human Chr (Location)		1p13.2; chr1:115127196-115212732 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(430) : Targeted(2) Gene trapped(428)

Gene Ontology (GO) classifications

All GO classifications: (4 annotations)

Process	biological_process
Component	cellular_component
Function	guanyl-nucleotide exchange factor activity, Rab guanyl-nucleotide exchange factor activity

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (63)    Tissues (8)    Images (24)
Theiler Stages: 22, 23, 28

Assay Type	Results
RNA in situ	59
RT-PCR	4

cDNA source data(22)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(23) cDNA(22) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000037717 (Evidence)
Ensembl Gene Model	ENSMUSG00000007379 (Evidence)
Entrez Gene	329727 (Evidence)
UniGene	293641
DFCI	TC1584257, TC1592145, TC1676728
DoTS	DT.101128247, DT.101280749, DT.91318675, DT.91329819, DT.94196546
NIA Mouse Gene Index	U003658
Consensus CDS Project	CCDS38572.2
International Mouse Knockout Project Status	Dennd2c

Sequences

Length	Strain/Species
genomic	OTTMUSG00000037717	VEGA Gene Model | MGI Sequence Detail	67166	C57BL/6J
transcript	OTTMUST00000097409	VEGA | MGI Sequence Detail	4979	Not Applicable
polypeptide	OTTMUSP00000054633	VEGA | MGI Sequence Detail	920	Not Applicable

All sequences(43) RefSeq(2) UniProt(5)

Polymorphisms

SNPs(147 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR005112	dDENN domain
InterPro	IPR001194	DENN domain
InterPro	IPR005113	uDENN domain
Protein Ontology	PR:000032007	DENN domain-containing protein 2C

References

(Earliest) J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)