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Defb42 Gene Detail
Summary
  • Symbol
    Defb42
  • Name
    defensin beta 42
  • Feature Type
    protein coding gene
  • IDs
    MGI:3033850
    NCBI Gene: 619548
Location & Maps
more
  • Sequence Map
    Chr14:63046991-63058149 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11159 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 33.24 cM, cytoband C3
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    DEFB136, defensin beta 136
  • Vertebrate Orthologs
    2
  • Human Ortholog
    DEFB136, defensin beta 136
    Orthology source: HGNC
  • Synonyms
    DEFB137
  • Links
    NCBI Gene ID: 613210
    neXtProt AC: NX_Q30KP8

  • Chr Location
    8p23.1; chr8:11973937-11974599 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
  • All Mutations and Alleles
    1
  • Chemically induced (other)
    1
  • Genomic Mutations
    1 involving Defb42
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020960 VEGA Gene Model | MGI Sequence Detail 11159 C57BL/6J ±  kb
transcript OTTMUST00000049556 VEGA | MGI Sequence Detail 618 Not Applicable  
polypeptide OTTMUSP00000022977 VEGA | MGI Sequence Detail 75 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    10 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000006412 beta-defensin 136
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 18
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:100553 Jalkanen J, et al., Discovery and characterization of new epididymis-specific beta-defensins in mice. Biochim Biophys Acta. 2005 Jul 25;1730(1):22-30
  • Latest
    J:156769 Amid C, et al., Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome. BMC Genomics. 2009;10:606

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory