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Mrgpra2b Gene Detail
Summary
  • Symbol
    Mrgpra2b
  • Name
    MAS-related GPR, member A2B
  • Synonyms
    MrgA2, Mrgpra2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3033098
    NCBI Gene: 235712
  • Gene Overview
    MyGene.info: MRGPRX3
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr7:47463799-47489585 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 30.86 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    12 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3033098
protein coding gene Chr7:47463799-47528862 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032285
protein coding gene Chr7:47906686-47960601 (-)
A/J MGP_AJ_G0032264
protein coding gene Chr7:46829914-47113736 (-)
AKR/J MGP_AKRJ_G0032200
protein coding gene Chr7:48101505-48433778 (-)
BALB/cJ MGP_BALBcJ_G0032276
protein coding gene Chr7:46761773-46984935 (-)
C3H/HeJ MGP_C3HHeJ_G0031989
protein coding gene Chr7:48554811-48837695 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032767
protein coding gene Chr7:50219803-50273830 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0031317
protein coding gene Chr7:40044378-40239760 (-)
CBA/J MGP_CBAJ_G0031954
protein coding gene Chr7:51689510-51957838 (-)
DBA/2J MGP_DBA2J_G0032111
protein coding gene Chr7:46413283-46624257 (-)
FVB/NJ MGP_FVBNJ_G0032065
protein coding gene Chr7:46389833-46445944 (-)
LP/J MGP_LPJ_G0032192
protein coding gene Chr7:48581967-48653468 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032102
protein coding gene Chr7:50601928-50672204 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032784
protein coding gene Chr7:47500820-47568415 (-)
PWK/PhJ MGP_PWKPhJ_G0021530
protein coding gene Chr16:9716479-9717646 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030879
protein coding gene Chr7:35325206-35347113 (-)
WSB/EiJ MGP_WSBEiJ_G0031437
protein coding gene Chr7:47791364-48031355 (-)



Homology
more
  • Human Ortholog
    MRGPRX3, MAS related GPR family member X3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    MRGPRX3, MAS related GPR family member X3
    Orthology source: HomoloGene
  • Synonyms
    GPCR, MRGX3, SNSR1, SNSR2
  • Links
    NCBI Gene ID: 117195
    neXtProt AC: NX_Q96LB0
    UniProt: Q96LB0

  • Chr Location
    11p15.1; chr11:18120955-18138480 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 235712 NCBI Gene Model | MGI Sequence Detail 25787 C57BL/6J ±  kb
transcript NM_153101 RefSeq | MGI Sequence Detail 1260 C57BL/6  
polypeptide Q91WW4 UniProt | EBI | MGI Sequence Detail 305 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 3
Other
Accession IDs
less
MGI:3802171
References
more
  • Summaries
    All 30
    Gene Ontology 1
    Phenotypes 9
  • Earliest
    J:71586 Dong X, et al., A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Cell. 2001 Sep 7;106(5):619-32
  • Latest
    J:277452 Meixiong J, et al., Identification of a bilirubin receptor that may mediate a component of cholestatic itch. Elife. 2019 Jan 21;8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory