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Or2y1g Gene Detail
Summary
  • Symbol
    Or2y1g
  • Name
    olfactory receptor family 2 subfamily Y member 1G
  • Synonyms
    GA_x6K02T2QP88-6154577-6153642, MOR256-24, MOR256-67_i, Olfr1393
  • Feature Type
    protein coding gene
  • IDs
    MGI:3031227
    NCBI Gene: 258463
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr11:49169131-49173596 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 29.31 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    110 from dbSNP Build 142
  • Strain Annotations
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3031227
protein coding gene Chr11:49154700-49183186 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0018194
protein coding gene Chr11:46526046-46527971 (+)
AKR/J MGP_AKRJ_G0018161
protein coding gene Chr11:47951613-47952662 (+)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0018614
protein coding gene Chr11:49833394-49854693 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0017949
protein coding gene Chr11:52141171-52148342 (+)
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0018132
protein coding gene Chr11:48738131-48738720 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018077
protein coding gene Chr11:53664481-53673781 (+)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    OR2Y1, olfactory receptor family 2 subfamily Y member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OR2Y1, olfactory receptor family 2 subfamily Y member 1
  • Synonyms
    OR5-2
  • Links
    NCBI Gene ID: 134083
    neXtProt AC: NX_Q8NGV0
    UniProt: Q8NGV0

  • Chr Location
    5q35.3; chr5:180739123-180740058 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit urinary glucose wasting and improved glucose tolerance.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000059864 Ensembl Gene Model | MGI Sequence Detail 4466 C57BL/6J ±  kb
    transcript ENSMUST00000078932 Ensembl | MGI Sequence Detail 936 Not Applicable  
    polypeptide ENSMUSP00000077962 Ensembl | MGI Sequence Detail 311 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR017452 GPCR, rhodopsin-like, 7TM
      IPR000276 G protein-coupled receptor, rhodopsin-like
      IPR000725 Olfactory receptor
    Molecular
    Reagents
    less
    • All nucleic 2
      cDNA 2

      Microarray probesets 1
    References
    more
    • Summaries
      All 18
      Gene Ontology 1
      Phenotypes 6
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:317732 Schiazza AR, et al., Loss of renal olfactory receptor 1393 leads to improved glucose homeostasis in a type 1 diabetic mouse model. Physiol Rep. 2021 Dec;9(23):e15007

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    09/27/2022
    MGI 6.21
    The Jackson Laboratory