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Olfr749 Gene Detail
Summary
  • Symbol
    Olfr749
  • Name
    olfactory receptor 749
  • Synonyms
    GA_x6K02T2PMLR-6484046-6483105, MOR106-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3030583
    NCBI Gene: 56858
  • Gene Overview
    MyGene.info: OR11H4
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr14:50736219-50744324 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 26.22 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    135 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3030583
protein coding gene Chr14:50736171-50745094 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0021209
protein coding gene Chr14:43347761-43355784 (-)
AKR/J MGP_AKRJ_G0021184
protein coding gene Chr14:44975558-44983642 (-)
BALB/cJ MGP_BALBcJ_G0021211
protein coding gene Chr14:43460841-43470464 (-)
C3H/HeJ MGP_C3HHeJ_G0020991
protein coding gene Chr14:44726128-44727190 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021648
protein coding gene Chr14:46493143-46501238 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022579
protein coding gene Chr19:2725326-2726337 (-)
CAST/EiJ MGP_CASTEiJ_G0020518
protein coding gene Chr14:41851661-41859776 (-)
CBA/J no annotation
DBA/2J MGP_DBA2J_G0021084
protein coding gene Chr14:43244244-43252860 (-)
FVB/NJ MGP_FVBNJ_G0021066
protein coding gene Chr14:42871756-42879892 (-)
LP/J MGP_LPJ_G0021153
protein coding gene Chr14:44959971-44968081 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021093
protein coding gene Chr14:47367273-47368249 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021678
protein coding gene Chr14:44470416-44478820 (-)
PWK/PhJ MGP_PWKPhJ_G0020268
protein coding gene Chr14:40140484-40150106 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020093
protein coding gene Chr14:40625551-40633074 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    OR11H4, olfactory receptor family 11 subfamily H member 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    OR11H4, olfactory receptor family 11 subfamily H member 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    OR14-36
  • Links
    NCBI Gene ID: 390442
    neXtProt AC: NX_Q8NGC9
    UniProt: Q8NGC9

  • Chr Location
    14q11.2; chr14:20242792-20243766 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
A reporter allele shows expression of this olfactory receptor by embryonic day 15.5 and throughout olfactory development there is an increase in the numbers of expressing olfactory sensory neurons with expression localized to the dorsal main olfactory epithelium.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 56858 NCBI Gene Model | MGI Sequence Detail 8106 C57BL/6J ±  kb
transcript NM_020288 RefSeq | MGI Sequence Detail 1021 C57BL/6  
polypeptide NP_064684 RefSeq | MGI Sequence Detail 313 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR017452 GPCR, rhodopsin-like, 7TM
    IPR000276 G protein-coupled receptor, rhodopsin-like
    IPR000725 Olfactory receptor
Molecular
Reagents
less

  • Microarray probesets 2
References
more
  • Summaries
    All 17
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:64950 Malnic B, et al., Combinatorial receptor codes for odors. Cell. 1999 Mar 5;96(5):713-23
  • Latest
    J:221945 Bressel OC, et al., Linear correlation between the number of olfactory sensory neurons expressing a given mouse odorant receptor gene and the total volume of the corresponding glomeruli in the olfactory bulb. J Comp Neurol. 2016 Jan 1;524(1):199-209

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory