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Zfp281
Gene Detail
 Symbol
Name
ID
Zfp281
zinc finger protein 281
MGI:3029290
Synonyms MGC:70044, MGC:7737
Feature Type protein coding gene
Genetic Map
Chromosome 1
59.93 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr1:136624901-136630053 bp, + strand
From VEGA annotation of GRCm38

  5153 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8270  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Zfp281

Human
homologs
Human Homolog ZNF281, zinc finger protein 281
NCBI Gene ID 23528
neXtProt AC  NX_Q9Y2X9
Human Synonyms  ZBP-99, ZNP-99
Human Chr (Location)  1q32.1; chr1:200404947-200410058 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from APF )
 
Mice homozygous for a knock-out allele exhibit embryonic lethality between E7.5 and E8.5.
 
Interactions
Zfp281 interacts with 388 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process cell differentiation, embryonic body morphogenesis, ...
Component nucleus
Function core promoter binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (83)    Tissues (48)    Images (22)
Theiler Stages: 15, 17, 18, 19, 21, 22, 23
Assay TypeResults
RNA in situ 83
cDNA source data(8)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(8) cDNA(8)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000022094 (Evidence)
Ensembl Gene ModelENSMUSG00000041483 (Evidence)
Entrez Gene226442 (Evidence)
DFCITC1578570, TC1601479
DoTSDT.101407848, DT.485400, DT.97364556
Consensus CDS ProjectCCDS15327.1
International Mouse Knockout Project StatusZfp281
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022094 VEGA Gene Model | MGI Sequence Detail 5153 C57BL/6J ±  kb
transcript OTTMUST00000052461 VEGA | MGI Sequence Detail 4933 Not Applicable 
polypeptide OTTMUSP00000024877 VEGA | MGI Sequence Detail 893 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(8) UniProt(2)
Polymorphisms SNPs within 2kb(11 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000017804 zinc finger protein 281
References (Earliest) J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
(Latest) J:204621 Gagliardi A, et al., A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal. EMBO J. 2013 Aug 14;32(16):2231-47
All references(37)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory