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Dhx37 Gene Detail
Summary
  • Symbol
    Dhx37
  • Name
    DEAH (Asp-Glu-Ala-His) box polypeptide 37
  • Synonyms
    LOC208144, LOC381671, MGC:90028
  • Feature Type
    protein coding gene
  • IDs
    MGI:3028576
    NCBI Gene: 208144
Location & Maps
more
  • Sequence Map
    Chr5:125413858-125434121 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      20264 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 64.20 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    DHX37, DEAH-box helicase 37
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DHX37, DEAH-box helicase 37
    Orthology source: HomoloGene
  • Synonyms
    DDX37
  • Links
    NCBI Gene ID: 57647
    neXtProt AC: NX_Q8IY37

  • Chr Location
    12q24.31; chr12:124946824-124989131 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 6641
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: DHX37
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Dhx37
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000055051 VEGA Gene Model | MGI Sequence Detail 20264 C57BL/6J ±  kb
transcript OTTMUST00000136375 VEGA | MGI Sequence Detail 4760 Not Applicable  
polypeptide OTTMUSP00000071998 VEGA | MGI Sequence Detail 1150 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    135 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • InterPro Domains
    IPR011545 DEAD/DEAH box helicase domain
    IPR011709 Domain of unknown function DUF1605
    IPR007502 Helicase-associated domain
    IPR001650 Helicase, C-terminal
    IPR014001 Helicase superfamily 1/2, ATP-binding domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
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  • All nucleic 22
    cDNA 22

    Microarray probesets 2
Other
Accession IDs
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MGI:2685297, MGI:2685896
References
more
  • Summaries
    All 22
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:91812 Stryke D, et al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Res. 2003 Jan 1;31(1):278-81
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory