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Dhx37 Gene Detail
Summary
  • Symbol
    Dhx37
  • Name
    DEAH (Asp-Glu-Ala-His) box polypeptide 37
  • Synonyms
    LOC208144, LOC381671, MGC:90028
  • Feature Type
    protein coding gene
  • IDs
    MGI:3028576
    NCBI Gene: 208144
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:125413858-125434121 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 64.20 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    135 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3028576
protein coding gene Chr5:125413747-125434145 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030111
protein coding gene Chr5:129259664-129287851 (-)
A/J MGP_AJ_G0030077
protein coding gene Chr5:123845105-123865344 (-)
AKR/J MGP_AKRJ_G0030012
protein coding gene Chr5:127865079-127885314 (-)
BALB/cJ MGP_BALBcJ_G0030088
protein coding gene Chr5:125180307-125200589 (-)
C3H/HeJ MGP_C3HHeJ_G0029805
protein coding gene Chr5:128468832-128489101 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030541
protein coding gene Chr5:134260019-134280230 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027766
protein coding gene Chr5:118382185-118402705 (-)
CAST/EiJ MGP_CASTEiJ_G0029214
protein coding gene Chr5:127608209-127628264 (-)
CBA/J MGP_CBAJ_G0029775
protein coding gene Chr5:139528904-139549135 (-)
DBA/2J MGP_DBA2J_G0029925
protein coding gene Chr5:123862586-123882886 (-)
FVB/NJ MGP_FVBNJ_G0029881
protein coding gene Chr5:122939187-122960815 (-)
LP/J MGP_LPJ_G0030014
protein coding gene Chr5:129780376-129804753 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029912
protein coding gene Chr5:143038487-143059938 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030582
protein coding gene Chr5:127478254-127499949 (-)
PWK/PhJ MGP_PWKPhJ_G0028928
protein coding gene Chr5:122704122-122724395 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028765
protein coding gene Chr5:125112064-125133842 (-)
WSB/EiJ MGP_WSBEiJ_G0029288
protein coding gene Chr5:128181016-128200118 (-)



Homology
more
  • Human Ortholog
    DHX37, DEAH-box helicase 37
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DHX37, DEAH-box helicase 37
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DDX37, Dhr1
  • Links
    NCBI Gene ID: 57647
    neXtProt AC: NX_Q8IY37
    UniProt: Q8IY37

  • Chr Location
    12q24.31; chr12:124946824-124989125 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 6641
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DHX37
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029480 Ensembl Gene Model | MGI Sequence Detail 20264 C57BL/6J ±  kb
transcript ENSMUST00000169485 Ensembl | MGI Sequence Detail 4760 Not Applicable  
polypeptide ENSMUSP00000131734 Ensembl | MGI Sequence Detail 1150 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • PDB
  • InterPro Domains
    IPR011545 DEAD/DEAH box helicase domain
    IPR011709 Domain of unknown function DUF1605
    IPR007502 Helicase-associated domain
    IPR001650 Helicase, C-terminal
    IPR014001 Helicase superfamily 1/2, ATP-binding domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 23
    cDNA 23

    Microarray probesets 2
Other
Accession IDs
less
MGI:2685297, MGI:2685896
References
more
  • Summaries
    All 28
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory