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Wee2 Gene Detail
Summary
  • Symbol
    Wee2
  • Name
    WEE1 homolog 2 (S. pombe)
  • Synonyms
    LOC381759, Wee1b
  • Feature Type
    protein coding gene
  • IDs
    MGI:3027899
    NCBI Gene: 381759
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr6:40439088-40466813 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 18.82 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    139 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3027899
protein coding gene Chr6:40435246-40466815 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030607
protein coding gene Chr6:38897354-38927152 (+)
A/J MGP_AJ_G0030580
protein coding gene Chr6:37187351-37222481 (+)
AKR/J MGP_AKRJ_G0030507
protein coding gene Chr6:38361946-38394882 (+)
BALB/cJ MGP_BALBcJ_G0030590
protein coding gene Chr6:37400266-37427962 (+)
C3H/HeJ MGP_C3HHeJ_G0030303
protein coding gene Chr6:38388574-38417587 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031044
protein coding gene Chr6:39863960-39891121 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028256
protein coding gene Chr6:35056881-35083930 (+)
CAST/EiJ MGP_CASTEiJ_G0029705
protein coding gene Chr6:38313326-38342556 (+)
CBA/J MGP_CBAJ_G0030281
protein coding gene Chr6:41456317-41487553 (+)
DBA/2J MGP_DBA2J_G0030425
protein coding gene Chr6:36996918-37024323 (+)
FVB/NJ MGP_FVBNJ_G0030379
protein coding gene Chr6:36781296-36812152 (+)
LP/J MGP_LPJ_G0030512
protein coding gene Chr6:38904507-38933044 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030415
protein coding gene Chr6:43694946-43727513 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031074
protein coding gene Chr6:38330637-38368899 (+)
PWK/PhJ MGP_PWKPhJ_G0029419
protein coding gene Chr6:36695320-36723139 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029255
protein coding gene Chr6:38047718-38082475 (+)
WSB/EiJ MGP_WSBEiJ_G0029781
protein coding gene Chr6:38279810-38307090 (+)



Homology
more
  • Human Ortholog
    WEE2, WEE2 oocyte meiosis inhibiting kinase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    WEE2, WEE2 oocyte meiosis inhibiting kinase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    OOMD5, WEE1B
  • Links
    NCBI Gene ID: 494551
    neXtProt AC: NX_P0C1S8
    UniProt: P0C1S8

  • Chr Location
    7q34; chr7:141708353-141731271 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037159 Ensembl Gene Model | MGI Sequence Detail 27726 C57BL/6J ±  kb
transcript ENSMUST00000038907 Ensembl | MGI Sequence Detail 2884 Not Applicable  
polypeptide ENSMUSP00000038754 Ensembl | MGI Sequence Detail 555 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 77
    cDNA 74
    Primer pair 2
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2685911
References
more
  • Summaries
    All 36
    Developmental Gene Expression 6
    Gene Ontology 9
    Phenotypes 2
  • Earliest
    J:87924 Nakanishi M, et al., Identification and characterization of human Wee1B, a new member of the Wee1 family of Cdk-inhibitory kinases. Genes Cells. 2000 Oct;5(10):839-47
  • Latest
    J:282460 Rong Y, et al., ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation. Nucleic Acids Res. 2019 Dec 2;47(21):11387-11402

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory