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Ppp4r2 Gene Detail
Summary
  • Symbol
    Ppp4r2
  • Name
    protein phosphatase 4, regulatory subunit 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3027896
    NCBI Gene: 232314
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:100833634-100869934 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 46.93 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    141 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3027896
protein coding gene Chr6:100833622-100869934 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0031057
protein coding gene Chr6:98943104-98978775 (+)
AKR/J MGP_AKRJ_G0030988
protein coding gene Chr6:101655814-101694112 (+)
BALB/cJ MGP_BALBcJ_G0031068
protein coding gene Chr6:98927577-98945832 (+)
C3H/HeJ MGP_C3HHeJ_G0030640
protein coding gene Chr6:82732351-82747679 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031527
protein coding gene Chr6:105483773-105527994 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028691
protein coding gene Chr6:96743701-96781212 (+)
CAST/EiJ MGP_CASTEiJ_G0030175
protein coding gene Chr6:101914955-101964610 (+)
CBA/J MGP_CBAJ_G0030754
protein coding gene Chr6:109534868-109549156 (+)
DBA/2J MGP_DBA2J_G0030907
protein coding gene Chr6:98063239-98100237 (+)
FVB/NJ MGP_FVBNJ_G0030861
protein coding gene Chr6:97264809-97288791 (+)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0030895
protein coding gene Chr6:113285134-113301824 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031554
protein coding gene Chr6:101564729-101608350 (+)
PWK/PhJ MGP_PWKPhJ_G0029891
protein coding gene Chr6:97107973-97123494 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029719
protein coding gene Chr6:100452070-100490523 (+)
WSB/EiJ MGP_WSBEiJ_G0030259
protein coding gene Chr6:102102356-102117003 (+)



Homology
more
  • Human Ortholog
    PPP4R2, protein phosphatase 4 regulatory subunit 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PPP4R2, protein phosphatase 4 regulatory subunit 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PP4R2
  • Links
    NCBI Gene ID: 151987
    neXtProt AC: NX_Q9NY27
    UniProt: Q9NY27

  • Chr Location
    3p13; chr3:72996743-73069201 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 232314 NCBI Gene Model | MGI Sequence Detail 36301 C57BL/6J ±  kb
    transcript NM_182939 RefSeq | MGI Sequence Detail 3641 C57BL/6  
    polypeptide Q0VGB7 UniProt | EBI | MGI Sequence Detail 417 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • Protein Ontology
      PR:000013155 serine/threonine-protein phosphatase 4 regulatory subunit 2
    • InterPro Domains
      IPR015267 Protein phosphatase 4 core regulatory subunit R2
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:3034166
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 10
    • Earliest
      J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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    Funding Information
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    last database update
    10/08/2019
    MGI 6.14
    The Jackson Laboratory