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Ppp4r2 Gene Detail
Summary
  • Symbol
    Ppp4r2
  • Name
    protein phosphatase 4, regulatory subunit 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3027896
    NCBI Gene: 232314
Location & Maps
more
  • Sequence Map
    Chr6:100833622-100869934 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      36313 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 46.93 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    PPP4R2, protein phosphatase 4 regulatory subunit 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PPP4R2, protein phosphatase 4 regulatory subunit 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    PP4R2
  • Links
    NCBI Gene ID: 151987
    neXtProt AC: NX_Q9NY27

  • Chr Location
    3p13; chr3:72996968-73065860 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    11
  • Gene trapped
    5
  • Spontaneous
    1
  • Targeted
    5
  • Genomic Mutations
    1 involving Ppp4r2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000057214 VEGA Gene Model | MGI Sequence Detail 36313 C57BL/6J ±  kb
transcript OTTMUST00000140855 VEGA | MGI Sequence Detail 4874 Not Applicable  
polypeptide OTTMUSP00000073702 VEGA | MGI Sequence Detail 417 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    141 from dbSNP Build 142
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR015267 Protein phosphatase 4 core regulatory subunit R2
Molecular
Reagents
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  • All nucleic 12
    cDNA 12

    Microarray probesets 5
Other
Accession IDs
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MGI:3034166
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory