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Bpifc Gene Detail
Summary
  • Symbol
    Bpifc
  • Name
    BPI fold containing family C
  • Synonyms
    Bpil2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3026884
    NCBI Gene: 270757
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:85959340-86011889 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 41.83 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    204 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3026884
protein coding gene Chr10:85959340-86011895 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017606
protein coding gene Chr10:86903831-86958242 (-)
A/J MGP_AJ_G0017586
protein coding gene Chr10:84009485-84061992 (-)
AKR/J MGP_AKRJ_G0017546
protein coding gene Chr10:86363388-86415885 (-)
BALB/cJ MGP_BALBcJ_G0017549
protein coding gene Chr10:84236755-84290837 (-)
C3H/HeJ MGP_C3HHeJ_G0017372
protein coding gene Chr10:86388640-86441175 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018006
protein coding gene Chr10:89861776-89914265 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015690
protein coding gene Chr10:79836978-79891802 (-)
CAST/EiJ MGP_CASTEiJ_G0016938
protein coding gene Chr10:86247999-86310188 (-)
CBA/J MGP_CBAJ_G0017341
protein coding gene Chr10:93570177-93628931 (-)
DBA/2J MGP_DBA2J_G0017448
protein coding gene Chr10:83122059-83174588 (-)
FVB/NJ MGP_FVBNJ_G0017441
protein coding gene Chr10:82388665-82441629 (-)
LP/J MGP_LPJ_G0017520
protein coding gene Chr10:87580171-87634064 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017469
protein coding gene Chr10:95209545-95262030 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018043
protein coding gene Chr10:86233086-86285598 (-)
PWK/PhJ MGP_PWKPhJ_G0016719
protein coding gene Chr10:83125973-83181085 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016508
protein coding gene Chr10:84878753-84936177 (-)
WSB/EiJ MGP_WSBEiJ_G0016996
protein coding gene Chr10:86192564-86251722 (-)



Homology
more
  • Human Ortholog
    BPIFC, BPI fold containing family C
  • Vertebrate Orthologs
    8
  • Human Ortholog
    BPIFC, BPI fold containing family C
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BPIL2
  • Links
    NCBI Gene ID: 254240
    neXtProt AC: NX_Q8NFQ6
    UniProt: Q8NFQ6

  • Chr Location
    22q12.3; chr22:32413845-32464465 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 270757 NCBI Gene Model | MGI Sequence Detail 52550 C57BL/6J ±  kb
transcript NM_177772 RefSeq | MGI Sequence Detail 2328 C57BL/6  
polypeptide Q8C186 UniProt | EBI | MGI Sequence Detail 509 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000004796 BPI fold-containing family C protein
  • InterPro Domains
    IPR017943 Bactericidal permeability-increasing protein, alpha/beta domain superfamily
    IPR032950 BPI fold-containing family C protein
    IPR032942 BPI/LBP/Plunc family
    IPR030675 Lipid binding protein BPI/LBP
    IPR017954 Lipid-binding serum glycoprotein, conserved site
    IPR001124 Lipid-binding serum glycoprotein, C-terminal
    IPR017942 Lipid-binding serum glycoprotein, N-terminal
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 30
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/19/2020
MGI 6.15
The Jackson Laboratory