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Flrt1 Gene Detail
Summary
  • Symbol
    Flrt1
  • Name
    fibronectin leucine rich transmembrane protein 1
  • Synonyms
    D630040I23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3026647
    NCBI Gene: 396184
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr19:7092014-7105729 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 5.20 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    272 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3026647
protein coding gene Chr19:7087464-7166030 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024784
protein coding gene Chr19:4207874-4222211 (-)
A/J MGP_AJ_G0024751
protein coding gene Chr19:3860359-3874013 (-)
AKR/J MGP_AKRJ_G0024724
protein coding gene Chr19:3991692-4006591 (-)
BALB/cJ MGP_BALBcJ_G0024751
protein coding gene Chr19:3978307-3992259 (-)
C3H/HeJ MGP_C3HHeJ_G0024519
protein coding gene Chr19:4118062-4131718 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025197
protein coding gene Chr19:4293382-4307078 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022631
protein coding gene Chr19:3761716-3775789 (-)
CAST/EiJ MGP_CASTEiJ_G0023991
protein coding gene Chr19:4019560-4033297 (-)
CBA/J MGP_CBAJ_G0024491
protein coding gene Chr19:4355916-4372664 (-)
DBA/2J MGP_DBA2J_G0024618
protein coding gene Chr19:3829123-3842732 (-)
FVB/NJ MGP_FVBNJ_G0024583
protein coding gene Chr19:3862323-3876508 (-)
LP/J MGP_LPJ_G0024704
protein coding gene Chr19:4062216-4075823 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024613
protein coding gene Chr19:4258251-4271932 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025245
protein coding gene Chr19:4125905-4140456 (-)
PWK/PhJ MGP_PWKPhJ_G0023737
protein coding gene Chr19:3876312-3890130 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023541
protein coding gene Chr19:3937741-3951476 (-)
WSB/EiJ MGP_WSBEiJ_G0024053
protein coding gene Chr19:4032189-4047352 (-)



Homology
more
  • Human Ortholog
    FLRT1, fibronectin leucine rich transmembrane protein 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FLRT1, fibronectin leucine rich transmembrane protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SPG68
  • Links
    NCBI Gene ID: 23769
    neXtProt AC: NX_Q9NZU1
    UniProt: Q9NZU1

  • Chr Location
    11q13.1; chr11:64035970-64119183 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
No notable phenotype was detected in a high-throughput screen of homozygous mice.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047787 Ensembl Gene Model | MGI Sequence Detail 13716 C57BL/6J ±  kb
transcript ENSMUST00000113383 Ensembl | MGI Sequence Detail 5859 Not Applicable  
polypeptide ENSMUSP00000109010 Ensembl | MGI Sequence Detail 674 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    Genomic 1
    cDNA 8
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2147754
References
more
  • Summaries
    All 34
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:257654 Memic F, et al., Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory