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Nr1h5 Gene Detail
Summary
  • Symbol
    Nr1h5
  • Name
    nuclear receptor subfamily 1, group H, member 5
  • Synonyms
    FXRB
  • Feature Type
    protein coding gene
  • IDs
    MGI:3026618
    NCBI Gene: 381463
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:102939658-102964133 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 45.25 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    150 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3026618
protein coding gene Chr3:102939658-102964286 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027686
protein coding gene Chr3:104183755-104211459 (-)
A/J MGP_AJ_G0027645
protein coding gene Chr3:100865651-100890131 (-)
AKR/J MGP_AKRJ_G0027611
protein coding gene Chr3:103355450-103382741 (-)
BALB/cJ MGP_BALBcJ_G0027658
protein coding gene Chr3:100645101-100669853 (-)
C3H/HeJ MGP_C3HHeJ_G0027387
protein coding gene Chr3:103674416-103700310 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028101
protein coding gene Chr3:108052981-108077109 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025442
protein coding gene Chr3:97009277-97034901 (-)
CAST/EiJ MGP_CASTEiJ_G0026844
protein coding gene Chr3:102785030-102812991 (-)
CBA/J MGP_CBAJ_G0027362
protein coding gene Chr3:111732832-111761974 (-)
DBA/2J MGP_DBA2J_G0027505
protein coding gene Chr3:100125957-100150510 (-)
FVB/NJ MGP_FVBNJ_G0027473
protein coding gene Chr3:98057368-98081622 (-)
LP/J MGP_LPJ_G0027612
protein coding gene Chr3:105519551-105543758 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027502
protein coding gene Chr3:117905550-117931393 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028156
protein coding gene Chr3:102863087-102887350 (-)
PWK/PhJ MGP_PWKPhJ_G0026570
protein coding gene Chr3:99863264-99887898 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026392
protein coding gene Chr3:100960801-100984857 (-)
WSB/EiJ MGP_WSBEiJ_G0026923
protein coding gene Chr3:103432597-103456833 (-)



Homology
more
  • Human Ortholog
    NR1H5P, nuclear receptor subfamily 1 group H member 5, pseudogene
  • Vertebrate Orthologs
    5
  • Human Ortholog
    NR1H5P, nuclear receptor subfamily 1 group H member 5, pseudogene
    Orthology source: HGNC
  • Synonyms
    Fxrb, NR1H5
  • Links
    NCBI Gene ID: 643609

  • Chr Location
    1p13.2; chr1:114834456-114851544 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000048938 Ensembl Gene Model | MGI Sequence Detail 24476 C57BL/6J ±  kb
transcript ENSMUST00000058899 Ensembl | MGI Sequence Detail 2835 Not Applicable  
polypeptide ENSMUSP00000052557 Ensembl | MGI Sequence Detail 505 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    11 Sequences
  • InterPro Domains
    IPR023257 Liver X receptor
    IPR001723 Nuclear hormone receptor
    IPR000536 Nuclear hormone receptor, ligand-binding domain
    IPR035500 Nuclear hormone receptor-like domain superfamily
    IPR013088 Zinc finger, NHR/GATA-type
    IPR001628 Zinc finger, nuclear hormone receptor-type
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 1
References
more
  • Summaries
    All 20
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory