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Scn4b
Gene Detail
 Symbol
Name
ID
Scn4b
sodium channel, type IV, beta
MGI:2687406
Synonyms LOC384934
Feature Type protein coding gene
Genetic Map
Chromosome 9
24.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:45138437-45154152 bp, + strand
From VEGA annotation of GRCm38

  15716 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18384  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Scn4b

Human
homologs
Human Homolog SCN4B, sodium channel, voltage-gated, type IV, beta subunit
NCBI Gene ID 6330
neXtProt AC  NX_Q8IWT1
Human Synonyms  ATFB17, LQT10, Navbeta4
Human Chr (Location)  11q23.3; chr11:118133377-118152915 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human SCN4B
Interactions
Scn4b interacts with 328 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (30 annotations)
Process AV node cell to bundle of His cell communication, cardiac muscle cell action potential involved in contraction, ...
Component integral component of membrane, intercalated disc, ...
Function ion channel binding, sodium channel activity, ...
External Resources: FuncBase
Expression
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) Genomic(1) cDNA(9)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000016701 (Evidence)
Ensembl Gene ModelENSMUSG00000046480 (Evidence)
Entrez Gene399548 (Evidence)
UniGene335112
DFCITC1642030, TC1678525
DoTSDT.101135184, DT.487499
NIA Mouse Gene IndexU068726
Consensus CDS ProjectCCDS23130.1
International Mouse Knockout Project StatusScn4b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016701 VEGA Gene Model | MGI Sequence Detail 15716 C57BL/6J ±  kb
transcript OTTMUST00000040454 VEGA | MGI Sequence Detail 4940 Not Applicable 
polypeptide OTTMUSP00000018078 VEGA | MGI Sequence Detail 228 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(98 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR013106 Immunoglobulin V-set
Protein Ontology PR:000014525 sodium channel subunit beta-4
References (Earliest) J:109029 Mulligan MK, et al., Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6368-73
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(27)
Other
accession IDs
MGI:2686317

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory