Scn4b
Gene Detail

Symbol Name ID

Scn4b sodium channel, type IV, beta MGI:2687406

Synonyms

LOC384934

Feature Type

protein coding gene

Genetic Map

Chromosome 9

24.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr9:45138437-45154152 bp, + strand From VEGA annotation of GRCm38   15716 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:18384  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Scn4b

Human homologs

Human Homolog		SCN4B, sodium channel, voltage-gated, type IV, beta subunit
NCBI Gene ID		6330
neXtProt AC		NX_Q8IWT1
Human Synonyms		LQT10, Navbeta4
Human Chr (Location)		11q23.3; chr11:118004092-118023630 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human SCN4B

Gene Ontology (GO) classifications

All GO classifications: (32 annotations)

Process	AV node cell to bundle of His cell communication, cardiac muscle contraction, ...
Component	integral to membrane, intercalated disc, ...
Function	ion channel activity, ion channel binding, ...

External Resources: FuncBase

Expression

cDNA source data(9)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(10) Genomic(1) cDNA(9)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000016701 (Evidence)
Ensembl Gene Model	ENSMUSG00000046480 (Evidence)
Entrez Gene	399548 (Evidence)
UniGene	335112
DFCI	TC1642030, TC1678525
DoTS	DT.101135184, DT.487499
NIA Mouse Gene Index	U068726
Consensus CDS Project	CCDS23130.1
International Mouse Knockout Project Status	Scn4b

Sequences

Length	Strain/Species
genomic	OTTMUSG00000016701	VEGA Gene Model | MGI Sequence Detail	15716	C57BL/6J
transcript	OTTMUST00000040454	VEGA | MGI Sequence Detail	4940	Not Applicable
polypeptide	OTTMUSP00000018078	VEGA | MGI Sequence Detail	228	Not Applicable

All sequences(24) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(62 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR007110	Immunoglobulin-like
InterPro	IPR013783	Immunoglobulin-like fold
InterPro	IPR003599	Immunoglobulin subtype
InterPro	IPR013106	Immunoglobulin V-set
Protein Ontology	PR:000014525	sodium channel subunit beta-4

References

(Earliest) J:109029 Mulligan MK, et al., Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6368-73
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(27)

Other accession IDs

MGI:2686317