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Kcnf1
Gene Detail
 Symbol
Name
ID
Kcnf1
potassium voltage-gated channel, subfamily F, member 1
MGI:2687399
Synonyms LOC382571, MGC:62472
Feature Type protein coding gene
Genetic Map
Chromosome 12
8.04 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr12:17172100-17176888 bp, - strand
From VEGA annotation of GRCm38

  4789 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:124236  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: potassium voltage-gated channel, alpha subunit, subfamilies A/C/D/F/G/S
Gene Tree: Kcnf1

Human
homologs
Human Homolog KCNF1, potassium voltage-gated channel, subfamily F, member 1
NCBI Gene ID 3754
neXtProt AC  NX_Q9H3M0
Human Synonyms  IK8, KCNF, kH1, KV5.1
Human Chr (Location)  2p25; chr2:10911937-10914225 (+)  GRCh38
Alleles
and
phenotypes
All alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process ion transport, potassium ion transmembrane transport, ...
Component integral component of membrane, membrane, ...
Function delayed rectifier potassium channel activity, ion channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (3)    Tissues (2)   
Theiler Stages: 25, 28
Assay TypeResults
RT-PCR 3
cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(8) cDNA(7) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000037668 (Evidence)
Ensembl Gene ModelENSMUSG00000051726 (Evidence)
Entrez Gene382571 (Evidence)
UniGene40173
DFCITC1645381, TC1710548
DoTSDT.91417507, DT.97394973
NIA Mouse Gene IndexU189941
Consensus CDS ProjectCCDS25825.2
International Mouse Knockout Project StatusKcnf1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037668 VEGA Gene Model | MGI Sequence Detail 4789 C57BL/6J ±  kb
transcript OTTMUST00000097263 VEGA | MGI Sequence Detail 4789 Not Applicable 
polypeptide OTTMUSP00000054524 VEGA | MGI Sequence Detail 505 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(95 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011333 BTB/POZ fold
InterPro IPR000210 BTB/POZ-like
InterPro IPR005821 Ion transport domain
InterPro IPR003131 Potassium channel tetramerisation-type BTB domain
InterPro IPR003968 Potassium channel, voltage dependent, Kv
InterPro IPR003971 Potassium channel, voltage dependent, Kv9
InterPro IPR003091 Voltage-dependent potassium channel
InterPro IPR027359 Voltage-dependent potassium channel, four helix bundle domain
Protein Ontology PR:000000724 voltage-gated potassium channel KCNF1
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:119550 Harrell MD, et al., Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. Physiol Genomics. 2007 Feb 12;28(3):273-83
All references(30)
Other
accession IDs
MGI:2686028

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory