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Pigs Gene Detail
Summary
  • Symbol
    Pigs
  • Name
    phosphatidylinositol glycan anchor biosynthesis, class S
  • Synonyms
    LOC245087, LOC276846
  • Feature Type
    protein coding gene
  • IDs
    MGI:2687325
    NCBI Gene: 276846
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:78219272-78233602 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 46.74 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    473 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2687325
 protein coding gene Chr11:78219241-78233608 (+)
129S1/SvImJ ENSMUSG00200049646
 protein coding gene Chr11:75336113-75350481 (+)
A/J ENSMUSG00195038250
 protein coding gene Chr11:75214914-75229287 (+)
AKR/J ENSMUSG00220046451
 protein coding gene Chr11:75438836-75453205 (+)
BALB/cJ ENSMUSG00180041094
 protein coding gene Chr11:75403691-75418062 (+)
C3H/HeJ ENSMUSG00175037688
 protein coding gene Chr11:75372923-75387291 (+)
C57BL/6NJ ENSMUSG00215041141
 protein coding gene Chr11:74996940-75011308 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016802
 protein coding gene Chr11:73267342-73286275 (+)
CAST/EiJ ENSTCUG00005044970
 protein coding gene Chr11:74896092-74909399 (+)
CBA/J ENSMUSG00210036435
 protein coding gene Chr11:75191355-75205722 (+)
DBA/2J ENSMUSG00185032970
 protein coding gene Chr11:75461379-75475747 (+)
FVB/NJ ENSMUSG00205031535
 protein coding gene Chr11:75290964-75305331 (+)
JF1/MsJ ENSUMUG00000030558
 protein coding gene Chr11:75840421-75855359 (+)
LP/J ENSMUSG00230044166
 protein coding gene Chr11:76491838-76506205 (+)
NOD/ShiLtJ ENSMUSG00190039258
 protein coding gene Chr11:75508433-75522801 (+)
NZO/HlLtJ ENSMUSG00225037045
 protein coding gene Chr11:78659326-78673693 (+)
PWK/PhJ ENSLUMG00010020192
 protein coding gene Chr11:75365660-75380494 (+)
SPRET/EiJ ENSMSPG00010034935
 protein coding gene Chr11:75776684-75790779 (+)
WSB/EiJ ENSIUOG00005029012
 protein coding gene Chr11:75346581-75361024 (+)



Homology
more
  • Human Ortholog
    PIGS, phosphatidylinositol glycan anchor biosynthesis class S
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PIGS, phosphatidylinositol glycan anchor biosynthesis class S
  • Synonyms
    DEE95, GPIBD18, PIG-S
  • Links
    NCBI Gene ID: 94005
    UniProt: Q96S52

  • Chr Location
    17q11.2; chr17:28553383-28571794 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human PIGS associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    694
  • Tissues
    97
  • cDNA Data
    84
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 276846 NCBI Gene Model | MGI Sequence Detail 14331 C57BL/6J ±  kb
transcript NM_201406 RefSeq | MGI Sequence Detail 2464 C57BL/6  
polypeptide Q6PD26 UniProt | EBI | MGI Sequence Detail 555 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000012706 GPI-anchor transamidase component PIGS
    (term hierarchy)
  • InterPro Domains
    IPR019540 Phosphatidylinositol-glycan biosynthesis class S protein
  • GlyGen
    Q6PD26 2 sites, 6 N-linked glycans (1 site)
Molecular
Reagents
less
  • All nucleic 84
    cDNA 84

    Microarray probesets 5
Other
Accession IDs
less
MGI:2685239, MGI:2685535
References
more
  • Summaries
    All 46
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 17
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:316399 LassegueI B, et al., Characterization of Poldip2 knockout mice: Avoiding incorrect gene targeting. PLoS One. 2021;16(12)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory