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Pigs Gene Detail
Summary
  • Symbol
    Pigs
  • Name
    phosphatidylinositol glycan anchor biosynthesis, class S
  • Synonyms
    LOC245087, LOC276846
  • Feature Type
    protein coding gene
  • IDs
    MGI:2687325
    NCBI Gene: 276846
  • Gene Overview
    MyGene.info: PIGS
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:78328422-78342776 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 46.74 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    42 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2687325
protein coding gene Chr11:78328415-78342782 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018776
protein coding gene Chr11:79325489-79344890 (+)
A/J MGP_AJ_G0018742
protein coding gene Chr11:76291736-76305400 (+)
AKR/J MGP_AKRJ_G0018712
protein coding gene Chr11:78597178-78611529 (+)
BALB/cJ MGP_BALBcJ_G0018716
protein coding gene Chr11:76700420-76715628 (+)
C3H/HeJ MGP_C3HHeJ_G0018529
protein coding gene Chr11:78637079-78652861 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019167
protein coding gene Chr11:81797240-81816006 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016802
protein coding gene Chr11:73267342-73286275 (+)
CAST/EiJ MGP_CASTEiJ_G0018083
protein coding gene Chr11:79086289-79107003 (+)
CBA/J MGP_CBAJ_G0018499
protein coding gene Chr11:85377421-85394058 (+)
DBA/2J MGP_DBA2J_G0018608
protein coding gene Chr11:75869898-75884165 (+)
FVB/NJ MGP_FVBNJ_G0018598
protein coding gene Chr11:75458880-75472637 (+)
LP/J MGP_LPJ_G0018679
protein coding gene Chr11:79858801-79873929 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018624
protein coding gene Chr11:85783355-85798393 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019207
protein coding gene Chr11:78844805-78860641 (+)
PWK/PhJ MGP_PWKPhJ_G0017854
protein coding gene Chr11:76658321-76678831 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017645
protein coding gene Chr11:78455741-78471730 (+)
WSB/EiJ MGP_WSBEiJ_G0018136
protein coding gene Chr11:78665320-78683845 (+)



Homology
more
  • Human Ortholog
    PIGS, phosphatidylinositol glycan anchor biosynthesis class S
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PIGS, phosphatidylinositol glycan anchor biosynthesis class S
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GPIBD18
  • Links
    NCBI Gene ID: 94005
    neXtProt AC: NX_Q96S52
    UniProt: Q96S52

  • Chr Location
    17q11.2; chr17:28553388-28571869 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41963
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PIGS
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 276846 NCBI Gene Model | MGI Sequence Detail 14355 C57BL/6J ±  kb
transcript NM_201406 RefSeq | MGI Sequence Detail 2505 C57BL/6  
polypeptide Q6PD26 UniProt | EBI | MGI Sequence Detail 555 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 84
    cDNA 84

    Microarray probesets 5
Other
Accession IDs
less
MGI:2685239, MGI:2685535
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory