Il1rapl1
Gene Detail

Symbol Name ID

Il1rapl1 interleukin 1 receptor accessory protein-like 1 MGI:2687319

Synonyms

6330532G10Rik, IL1R8, IL1RAPL, MRX34, OPHN4, TIGIRR-2

Feature Type

protein coding gene

Genetic Map

Chromosome X

39.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

ChrX:86740870-88115645 bp, - strand From VEGA annotation of GRCm38   1374776 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:8609  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Il1rapl1

Human homologs

Human Homolog		IL1RAPL1, interleukin 1 receptor accessory protein-like 1
NCBI Gene ID		11141
neXtProt AC		NX_Q9NZN1
Human Synonyms		IL1R8, IL1RAPL, MRX10, MRX21, MRX34, OPHN4, TIGIRR-2
Human Chr (Location)		Xp22.1-p21.3; chrX:28605681-29974017 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human IL1RAPL1

Alleles and phenotypes

All alleles(5) : Targeted(5)
 

Mice homozygous for a knock-out allele exhibit premature giant inhibitory postsynaptic currents and parallel fiber-mediated recruitment of molecular layer interneurons.

 

Gene Ontology (GO) classifications

All GO classifications: (22 annotations)

Process	heterophilic cell-cell adhesion, innate immune response, ...
Component	cell projection, cell surface, ...
Function	protein binding, receptor binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (201)    Tissues (33)    Images (27)
Theiler Stages: 23

Assay Type	Results
RNA in situ	201

cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(6) cDNA(6)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000016973 (Evidence)
Ensembl Gene Model	ENSMUSG00000052372 (Evidence)
Entrez Gene	331461 (Evidence)
DFCI	TC1608186, TC1618986
DoTS	DT.101704002, DT.91335490
NIA Mouse Gene Index	U039520
Consensus CDS Project	CCDS53128.1
International Mouse Knockout Project Status	Il1rapl1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000016973	VEGA Gene Model | MGI Sequence Detail	1374776	C57BL/6J
transcript	OTTMUST00000041160	VEGA | MGI Sequence Detail	9133	Not Applicable
polypeptide	OTTMUSP00000018440	VEGA | MGI Sequence Detail	696	Not Applicable

All sequences(28) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(1713 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR007110	Immunoglobulin-like
InterPro	IPR013783	Immunoglobulin-like fold
InterPro	IPR003599	Immunoglobulin subtype
InterPro	IPR003598	Immunoglobulin subtype 2
InterPro	IPR015621	Interleukin-1 receptor family
InterPro	IPR004075	Interleukin-1 receptor, type I/Toll precursor
InterPro	IPR000157	Toll/interleukin-1 receptor homology (TIR) domain
Protein Ontology	PR:000008992	X-linked interleukin-1 receptor accessory protein-like 1

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:177124 Yoshida T, et al., IL-1 receptor accessory protein-like 1 associated with mental retardation and autism mediates synapse formation by trans-synaptic interaction with protein tyrosine phosphatase delta. J Neurosci. 2011 Sep 21;31(38):13485-99
All references(34)

Other accession IDs

MGI:1923412