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Il1rapl1
Gene Detail
Symbol

Name
ID
Il1rapl1
interleukin 1 receptor accessory protein-like 1
MGI:2687319
Synonyms
6330532G10Rik, IL1R8, IL1RAPL, MRX34, OPHN4, TIGIRR-2
Feature Type
protein coding gene
Genetic Map
Chromosome X
39.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
ChrX:86740870-88115645 bp, - strand
From VEGA annotation of GRCm38

  1374776 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8609  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: IL1RAPL1
Gene Tree: Il1rapl1

Human
homologs
IL1RAPL1, interleukin 1 receptor accessory protein-like 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 11141
neXtProt AC: NX_Q9NZN1

Human Synonyms: IL1R8, IL1RAPL, MRX10, MRX21, MRX34, OPHN4, TIGIRR-2

Human Chr (Location): Xp22.1-p21.3; chrX:28587564-29956350 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human IL1RAPL1

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
 
Mice homozygous for a knock-out allele exhibit premature giant inhibitory postsynaptic currents and parallel fiber-mediated recruitment of molecular layer interneurons.
 
Interactions
Il1rapl1 interacts with 521 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (201)    Tissues (33)    Images (27)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 201
cDNA source data(7)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase il1rapl1 ; ZFIN il1rapl1a, il1rapl1b    NEW 
Molecular
reagents
All nucleic(7) cDNA(7)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000016973 (Evidence)
Ensembl Gene Model ENSMUSG00000052372 (Evidence)
Entrez Gene 331461 (Evidence)
DFCI TC1608186, TC1618986
DoTS DT.101704002, DT.87024974, DT.91335490
NIA Mouse Gene Index U039520
PDB 4YFC, 4YH6, 4YH7
Consensus CDS Project CCDS53128.1
International Mouse Phenotyping Consortium Status Il1rapl1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016973 VEGA Gene Model | MGI Sequence Detail 1374776 C57BL/6J ±  kb
transcript OTTMUST00000041160 VEGA | MGI Sequence Detail 9133 Not Applicable 
polypeptide OTTMUSP00000018440 VEGA | MGI Sequence Detail 696 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(3613 from dbSNP Build 137)    SNPs within 2kb including multiple locations(3629)
Protein-related
information
ResourceIDDescription
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR003598 Immunoglobulin subtype 2
InterPro IPR015621 Interleukin-1 receptor family
InterPro IPR000157 Toll/interleukin-1 receptor homology (TIR) domain
Protein Ontology PR:000008992 interleukin-1 receptor accessory protein-like 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:201324 Houbaert X, et al., Target-specific vulnerability of excitatory synapses leads to deficits in associative memory in a model of intellectual disorder. J Neurosci. 2013 Aug 21;33(34):13805-19
All references(33)
Other
accession IDs
MGI:1923412

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory