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Pld6
Gene Detail
Symbol

Name
ID
Pld6
phospholipase D family, member 6
MGI:2687283
Synonyms
4933433K01Rik, mitoPLD, Zuc
Feature Type
protein coding gene
Genetic Map
Chromosome 11
37.79 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:59783897-59787645 bp, - strand
From VEGA annotation of GRCm38

  3749 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Gene Tree: Pld6
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display male infertility with arrest of male meiosis and mitochondrial abnormalities.
 
Interactions
Pld6 interacts with 34 markers (Mir92-2, Mir100, Mir101a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (24 annotations)
Process cell differentiation, DNA methylation involved in gamete generation, ...
Component integral component of membrane, membrane, ...
Function catalytic activity, endonuclease activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(15)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(15)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000008093 (Evidence)
Ensembl Gene ModelENSMUSG00000043648 (Evidence)
Entrez Gene194908 (Evidence)
UniGene344651
DFCITC1584626
DoTSDT.40180176, DT.102547186
NIA Mouse Gene IndexU032855
EC3.1.-.-
PDB4GGK, 4GGJ
Consensus CDS ProjectCCDS70199.1
International Mouse Knockout Project StatusPld6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008093 VEGA Gene Model | MGI Sequence Detail 3749 C57BL/6J ±  kb
transcript OTTMUST00000018402 VEGA | MGI Sequence Detail 948 Not Applicable 
polypeptide OTTMUSP00000008460 VEGA | MGI Sequence Detail 221 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(5) UniProt(1)
Polymorphisms
SNPs within 2kb(47 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR025202 Phospholipase D-like domain
InterPro IPR001736 Phospholipase D/Transphosphatidylase
Protein Ontology PR:000012848 phospholipase D6
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:189220 Ipsaro JJ, et al., The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis. Nature. 2012 Nov 8;491(7423):279-83
All references(34)
Other
accession IDs
MGI:2684856

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory