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N4bp2l2
Gene Detail
 Symbol
Name
ID
N4bp2l2
NEDD4 binding protein 2-like 2
MGI:2687207
Synonyms 2700092H06Rik, MGC:25830, zag1
Feature Type protein coding gene
Genetic Map
Chromosome 5
89.57 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr5:150608007-150665612 bp, - strand
From VEGA annotation of GRCm38

  57606 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:115380  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: N4bp2l2

Human
homologs
Human Homolog N4BP2L2, NEDD4 binding protein 2-like 2
NCBI Gene ID 10443
neXtProt AC  NX_Q92802
Human Synonyms  92M18.3, CG005, PFAAP5
Human Chr (Location)  13q13.1; chr13:32432488-32542702 (-)  GRCh38
Alleles
and
phenotypes
All alleles(22) : Targeted(2) Gene trapped(20)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process blastocyst development, in utero embryonic development, ...
Component cytoplasm, extracellular vesicular exosome, ...
Function enzyme binding, protein binding, ...
External Resources: FuncBase
Expression
cDNA source data(48)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(48) cDNA(48)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000027925 (Evidence)
Ensembl Gene ModelENSMUSG00000029655 (Evidence)
Entrez Gene381695 (Evidence)
UniGene246934
DFCITC1585455, TC1602895, TC1613546, TC1637321, TC1707155
DoTSDT.101721631, DT.110690300, DT.110690339, DT.55212334, DT.55274551, DT.91334746
NIA Mouse Gene IndexU129649, U151441
Consensus CDS ProjectCCDS19888.2
International Mouse Knockout Project StatusN4bp2l2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027925 VEGA Gene Model | MGI Sequence Detail 57606 C57BL/6J ±  kb
transcript OTTMUST00000069171 VEGA | MGI Sequence Detail 8982 Not Applicable 
polypeptide OTTMUSP00000035096 VEGA | MGI Sequence Detail 575 Not Applicable 

For the selected sequences
All sequences(63) RefSeq(7) UniProt(4)
Polymorphisms SNPs within 2kb(235 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026568 NEDD4-binding protein 2-like 2
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000010940 NEDD4-binding protein 2-like 2
References (Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:205673 Salipante SJ, et al., Contributions to neutropenia from PFAAP5 (N4BP2L2), a novel protein mediating transcriptional repressor cooperation between Gfi1 and neutrophil elastase. Mol Cell Biol. 2009 Aug;29(16):4394-405
All references(35)
Other
accession IDs
MGI:1925575

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory