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N4bp2l2
Gene Detail
Symbol

Name
ID
N4bp2l2
NEDD4 binding protein 2-like 2
MGI:2687207
Synonyms
2700092H06Rik, MGC:25830, zag1
Feature Type
protein coding gene
Genetic Map
Chromosome 5
89.57 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr5:150608007-150665612 bp, - strand
From VEGA annotation of GRCm38

  57606 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:115380  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

HCOP human homology predictions: N4BP2L2
Gene Tree: N4bp2l2

Human
homologs
N4BP2L2, NEDD4 binding protein 2-like 2
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 10443
neXtProt AC: NX_Q92802

Human Synonyms: 92M18.3, CG005, PFAAP5

Human Chr (Location): 13q13.1; chr13:32432488-32538885 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(22) : Gene trapped(20) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
N4bp2l2 interacts with 473 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process blastocyst development, in utero embryonic development, ...
Component extracellular exosome, nucleus, ...
Function enzyme binding, protein binding, ...
External Resources: FuncBase
Expression
cDNA source data(48)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase n4bp2l2    NEW 
Molecular
reagents
All nucleic(48) cDNA(48)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000027925 (Evidence)
Ensembl Gene Model ENSMUSG00000029655 (Evidence)
Entrez Gene 381695 (Evidence)
UniGene 246934
DFCI TC1613546, TC1637321, TC1602895, TC1585455, TC1707155
DoTS DT.91334746, DT.55274551, DT.55212334, DT.101721631, DT.110690339, DT.110690300
NIA Mouse Gene Index U129649, U151441
Consensus CDS Project CCDS19888.2
International Mouse Phenotyping Consortium Status N4bp2l2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027925 VEGA Gene Model | MGI Sequence Detail 57606 C57BL/6J ±  kb
transcript OTTMUST00000069171 VEGA | MGI Sequence Detail 8982 Not Applicable 
polypeptide OTTMUSP00000035096 VEGA | MGI Sequence Detail 575 Not Applicable 

For the selected sequences
All sequences(60) RefSeq(4) UniProt(4)
Polymorphisms
SNPs within 2kb(235 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026568 NEDD4-binding protein 2-like 2
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000010940 NEDD4-binding protein 2-like 2
References
(Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:205673 Salipante SJ, et al., Contributions to neutropenia from PFAAP5 (N4BP2L2), a novel protein mediating transcriptional repressor cooperation between Gfi1 and neutrophil elastase. Mol Cell Biol. 2009 Aug;29(16):4394-405
All references(34)
Other
accession IDs
MGI:1925575

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory