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N4bp2l2 Gene Detail
Summary
  • Symbol
    N4bp2l2
  • Name
    NEDD4 binding protein 2-like 2
  • Synonyms
    2700092H06Rik, MGC:25830, zag1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2687207
    NCBI Gene: 381695
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:150608007-150666183 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 89.57 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    234 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2687207
protein coding gene Chr5:150599931-150666183 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030412
protein coding gene Chr5:156551129-156613392 (-)
A/J MGP_AJ_G0030385
protein coding gene Chr5:149842080-149900274 (-)
AKR/J MGP_AKRJ_G0030312
protein coding gene Chr5:154467359-154530002 (-)
BALB/cJ MGP_BALBcJ_G0030394
protein coding gene Chr5:151105431-151164487 (-)
C3H/HeJ MGP_C3HHeJ_G0030108
protein coding gene Chr5:155470176-155530363 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030849
protein coding gene Chr5:162265041-162323155 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028062
protein coding gene Chr5:144171312-144229154 (-)
CAST/EiJ MGP_CASTEiJ_G0029510
protein coding gene Chr5:155119204-155191728 (-)
CBA/J MGP_CBAJ_G0030086
protein coding gene Chr5:169106112-169165981 (-)
DBA/2J MGP_DBA2J_G0030230
protein coding gene Chr5:149493417-149551654 (-)
FVB/NJ MGP_FVBNJ_G0030184
protein coding gene Chr5:148738561-148796717 (-)
LP/J MGP_LPJ_G0030317
protein coding gene Chr5:157211322-157271234 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030220
protein coding gene Chr5:171162518-171222886 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030879
protein coding gene Chr5:154425802-154489632 (-)
PWK/PhJ MGP_PWKPhJ_G0029224
protein coding gene Chr5:148660826-148721082 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029060
protein coding gene Chr5:151711464-151772214 (-)
WSB/EiJ MGP_WSBEiJ_G0029587
protein coding gene Chr5:155236971-155298115 (-)



Homology
more
  • Human Ortholog
    N4BP2L2, NEDD4 binding protein 2 like 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    N4BP2L2, NEDD4 binding protein 2 like 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    92M18.3, CG005, CG016, PFAAP5
  • Links
    NCBI Gene ID: 10443
    neXtProt AC: NX_Q92802
    UniProt: Q92802

  • Chr Location
    13q13.1; chr13:32432488-32542710 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029655 Ensembl Gene Model | MGI Sequence Detail 58177 C57BL/6J ±  kb
transcript ENSMUST00000118316 Ensembl | MGI Sequence Detail 8982 Not Applicable  
polypeptide ENSMUSP00000113895 Ensembl | MGI Sequence Detail 575 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 52
    cDNA 52

    Microarray probesets 3
Other
Accession IDs
less
MGI:1925575
References
more
  • Summaries
    All 31
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:205673 Salipante SJ, et al., Contributions to neutropenia from PFAAP5 (N4BP2L2), a novel protein mediating transcriptional repressor cooperation between Gfi1 and neutrophil elastase. Mol Cell Biol. 2009 Aug;29(16):4394-405

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory