About   Help   FAQ
Fbxo10
Gene Detail
Symbol

Name
ID
Fbxo10
F-box protein 10
MGI:2686937
Synonyms
FBX10, LOC269529
Feature Type
protein coding gene
Genetic Map
Chromosome 4
23.68 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:45034247-45084604 bp, - strand
From VEGA annotation of GRCm38

  50358 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:19544  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Gene Tree: Fbxo10

Human
homologs
Human Homolog FBXO10, F-box protein 10
NCBI Gene ID 26267
neXtProt AC  NX_Q9UK96
Human Synonyms  FBX10, PRMT11
Human Chr (Location)  9p13.2; chr9:37510892-37576253 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(1) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Fbxo10 interacts with 273 markers (Mir7-2, Mir7b, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process apoptotic process, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, ...
Component cytoplasm
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(8)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(8) cDNA(8)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000007455 (Evidence)
Ensembl Gene ModelENSMUSG00000048232 (Evidence)
Entrez Gene269529 (Evidence)
DFCITC1581178, TC1612860
DoTSDT.101193161, DT.101338727, DT.40138882, DT.528190
NIA Mouse Gene IndexU025017
Consensus CDS ProjectCCDS51171.1
International Mouse Knockout Project StatusFbxo10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000007455 VEGA Gene Model | MGI Sequence Detail 50358 C57BL/6J ±  kb
transcript OTTMUST00000017247 VEGA | MGI Sequence Detail 4635 Not Applicable 
polypeptide OTTMUSP00000007967 VEGA | MGI Sequence Detail 950 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(200 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006633 Carbohydrate-binding/sugar hydrolysis domain
InterPro IPR001810 F-box domain, cyclin-like
InterPro IPR006626 Parallel beta-helix repeat
InterPro IPR022441 Parallel beta-helix repeat-2
InterPro IPR012334 Pectin lyase fold
InterPro IPR011050 Pectin lyase fold/virulence factor
Protein Ontology PR:000007387 F-box only protein 10
References
(Earliest) J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)
Other
accession IDs
MGI:2685480

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory