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Fbxo10 Gene Detail
Summary
  • Symbol
    Fbxo10
  • Name
    F-box protein 10
  • Synonyms
    FBX10, LOC269529
  • Feature Type
    protein coding gene
  • IDs
    MGI:2686937
    NCBI Gene: 269529
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:45034247-45084604 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 23.68 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    199 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2686937
protein coding gene Chr4:45034247-45084647 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028240
protein coding gene Chr4:43241844-43294131 (-)
A/J MGP_AJ_G0028197
protein coding gene Chr4:41699785-41751133 (-)
AKR/J MGP_AKRJ_G0028149
protein coding gene Chr4:42693539-42745746 (-)
BALB/cJ MGP_BALBcJ_G0028217
protein coding gene Chr4:41784202-41834459 (-)
C3H/HeJ MGP_C3HHeJ_G0027939
protein coding gene Chr4:43301873-43353921 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028658
protein coding gene Chr4:44884729-44934576 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025968
protein coding gene Chr4:39100958-39150634 (-)
CAST/EiJ MGP_CASTEiJ_G0027378
protein coding gene Chr4:42843329-42895491 (-)
CBA/J MGP_CBAJ_G0027905
protein coding gene Chr4:46264637-46320268 (-)
DBA/2J MGP_DBA2J_G0028054
protein coding gene Chr4:41598272-41649785 (-)
FVB/NJ MGP_FVBNJ_G0028021
protein coding gene Chr4:40822998-40875601 (-)
LP/J MGP_LPJ_G0028153
protein coding gene Chr4:43300290-43351475 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028045
protein coding gene Chr4:49419836-49469864 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028694
protein coding gene Chr4:42894689-42947173 (-)
PWK/PhJ MGP_PWKPhJ_G0027103
protein coding gene Chr4:41659881-41716023 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026931
protein coding gene Chr4:42414799-42466010 (-)
WSB/EiJ MGP_WSBEiJ_G0027456
protein coding gene Chr4:42779279-42830997 (-)



Homology
more
  • Human Ortholog
    FBXO10, F-box protein 10
  • Vertebrate Orthologs
    9
  • Human Ortholog
    FBXO10, F-box protein 10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FBX10, PRMT11
  • Links
    NCBI Gene ID: 26267
    neXtProt AC: NX_Q9UK96
    UniProt: Q9UK96

  • Chr Location
    9p13.2; chr9:37509920-37576459 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000048232 Ensembl Gene Model | MGI Sequence Detail 50358 C57BL/6J ±  kb
transcript ENSMUST00000052236 Ensembl | MGI Sequence Detail 4635 Not Applicable  
polypeptide ENSMUSP00000058233 Ensembl | MGI Sequence Detail 950 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 1
Other
Accession IDs
less
MGI:2685480
References
more
  • Summaries
    All 27
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:94083 Klarlund JK, et al., Signaling complexes of the FERM domain-containing protein GRSP1 bound to ARF exchange factor GRP1. J Biol Chem. 2001 Oct 26;276(43):40065-70
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory