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Tmprss7 Gene Detail
Summary
  • Symbol
    Tmprss7
  • Name
    transmembrane serine protease 7
  • Synonyms
    B230219I23Rik, LOC385645, matriptase-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2686594
    NCBI Gene: 208171
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:45476678-45514021 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 29.84 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1492 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2686594
 protein coding gene Chr16:45476672-45521822 (-)
129S1/SvImJ ENSMUSG00200021240
 protein coding gene Chr16:42358910-42397477 (-)
A/J ENSMUSG00195003325
 protein coding gene Chr16:41961519-42000150 (-)
AKR/J ENSMUSG00220022377
 protein coding gene Chr16:42313579-42359072 (-)
BALB/cJ ENSMUSG00180025878
 protein coding gene Chr16:42166455-42205081 (-)
C3H/HeJ ENSMUSG00175025480
 protein coding gene Chr16:42441189-42478537 (-)
C57BL/6NJ ENSMUSG00215005579
 protein coding gene Chr16:42261082-42298432 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020783
 protein coding gene Chr16:42811330-42849837 (-)
CAST/EiJ ENSTCUG00005012686
 protein coding gene Chr16:42644980-42683477 (-)
CBA/J ENSMUSG00210016481
 protein coding gene Chr16:42463334-42500671 (-)
DBA/2J ENSMUSG00185009976
 protein coding gene Chr16:42346107-42384731 (-)
FVB/NJ ENSMUSG00205011629
 protein coding gene Chr16:42211372-42249996 (-)
JF1/MsJ ENSUMUG00000015318
 protein coding gene Chr16:42576800-42614157 (-)
LP/J ENSMUSG00230024920
 protein coding gene Chr16:44912816-44952096 (-)
NOD/ShiLtJ ENSMUSG00190018531
 protein coding gene Chr16:42356980-42395562 (-)
NZO/HlLtJ ENSMUSG00225028766
 protein coding gene Chr16:48004515-48043802 (-)
PWK/PhJ ENSLUMG00010025660
 protein coding gene Chr16:42441012-42478023 (-)
SPRET/EiJ ENSMSPG00010006993
 protein coding gene Chr16:42617053-42655680 (-)
WSB/EiJ ENSIUOG00005013088
 protein coding gene Chr16:42534859-42573482 (-)



Homology
more
  • Human Ortholog
    TMPRSS7, transmembrane serine protease 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMPRSS7, transmembrane serine protease 7
  • Links
    NCBI Gene ID: 344805
    UniProt: Q7RTY8

  • Chr Location
    3q13.2; chr3:112034736-112081269 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    4
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033177 Ensembl Gene Model | MGI Sequence Detail 37344 C57BL/6J ±  kb
transcript ENSMUST00000114562 Ensembl | MGI Sequence Detail 2587 Not Applicable  
polypeptide ENSMUSP00000110209 Ensembl | MGI Sequence Detail 829 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:117598 Szabo R, et al., Matriptase-3 is a novel phylogenetically preserved membrane-anchored serine protease with broad serpin reactivity. Biochem J. 2005 Aug 15;390(Pt 1):231-42
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory