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Cfap57 Gene Detail
Summary
  • Symbol
    Cfap57
  • Name
    cilia and flagella associated protein 57
  • Synonyms
    1110020C03Rik, C130004B06Rik, LOC384050, Wdr65
  • Feature Type
    protein coding gene
  • IDs
    MGI:2686209
    NCBI Gene: 68625
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:118554550-118620766 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 54.84 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    530 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2686209
protein coding gene Chr4:118554550-118620777 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028673
protein coding gene Chr4:119617724-119690409 (-)
A/J MGP_AJ_G0028634
protein coding gene Chr4:114971000-115038014 (-)
AKR/J MGP_AKRJ_G0028584
protein coding gene Chr4:117504700-117571727 (-)
BALB/cJ MGP_BALBcJ_G0028655
protein coding gene Chr4:115611827-115676470 (-)
C3H/HeJ MGP_C3HHeJ_G0028369
protein coding gene Chr4:119063210-119131628 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029096
protein coding gene Chr4:124180021-124255463 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026380
protein coding gene Chr4:108984671-109056203 (-)
CAST/EiJ MGP_CASTEiJ_G0027803
protein coding gene Chr4:116322875-116397209 (-)
CBA/J MGP_CBAJ_G0028336
protein coding gene Chr4:127585247-127665371 (-)
DBA/2J MGP_DBA2J_G0028484
protein coding gene Chr4:115586638-115656912 (-)
FVB/NJ MGP_FVBNJ_G0028452
protein coding gene Chr4:114101031-114164967 (-)
LP/J MGP_LPJ_G0028586
protein coding gene Chr4:119792503-119868633 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028479
protein coding gene Chr4:132463190-132538936 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029133
protein coding gene Chr4:118644889-118712282 (-)
PWK/PhJ MGP_PWKPhJ_G0027529
protein coding gene Chr4:112412496-112492259 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027352
protein coding gene Chr4:114952844-115025393 (-)
WSB/EiJ MGP_WSBEiJ_G0027882
protein coding gene Chr4:118548175-118621635 (-)



Homology
more
  • Human Ortholog
    CFAP57, cilia and flagella associated protein 57
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CFAP57, cilia and flagella associated protein 57
    Orthology source: HomoloGene, HGNC
  • Synonyms
    VWS2, WDR65
  • Links
    NCBI Gene ID: 149465
    neXtProt AC: NX_Q96MR6
    UniProt: Q96MR6

  • Chr Location
    1p34.2; chr1:43172330-43254358 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68625 NCBI Gene Model | MGI Sequence Detail 66217 C57BL/6J ±  kb
    transcript NM_026789 RefSeq | MGI Sequence Detail 4010 C57BL/6  
    polypeptide Q9D180 UniProt | EBI | MGI Sequence Detail 1249 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 10
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1915875, MGI:1924381, MGI:2140512
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 2
      Phenotypes 12
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:174238 Rorick NK, et al., Genomic strategy identifies a missense mutation in WD-repeat domain 65 (WDR65) in an individual with Van der Woude syndrome. Am J Med Genet A. 2011 Jun;155A(6):1314-21

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    10/08/2019
    MGI 6.14
    The Jackson Laboratory