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Gpr25 Gene Detail
Summary
  • Symbol
    Gpr25
  • Name
    G protein-coupled receptor 25
  • Synonyms
    LOC383563
  • Feature Type
    protein coding gene
  • IDs
    MGI:2686146
    NCBI Gene: 383563
  • Gene Overview
    MyGene.info: GPR25
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:136259797-136260873 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 59.61 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    9 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2686146
protein coding gene Chr1:136258914-136260873 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016539
protein coding gene Chr1:140076513-140077589 (-)
A/J MGP_AJ_G0016522
protein coding gene Chr1:134767906-134768982 (-)
AKR/J MGP_AKRJ_G0016487
protein coding gene Chr1:138773625-138774701 (-)
BALB/cJ MGP_BALBcJ_G0016482
protein coding gene Chr1:135098652-135099728 (-)
C3H/HeJ MGP_C3HHeJ_G0016308
protein coding gene Chr1:138868179-138869255 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016943
protein coding gene Chr1:145094922-145095998 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014654
protein coding gene Chr1:127876524-127877600 (-)
CAST/EiJ MGP_CASTEiJ_G0015888
protein coding gene Chr1:137969443-137970519 (-)
CBA/J MGP_CBAJ_G0016281
protein coding gene Chr1:150126222-150127298 (-)
DBA/2J MGP_DBA2J_G0016387
protein coding gene Chr1:133761153-133762229 (-)
FVB/NJ MGP_FVBNJ_G0016386
protein coding gene Chr1:132410477-132411553 (-)
LP/J MGP_LPJ_G0016458
protein coding gene Chr1:141296218-141297294 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016411
protein coding gene Chr1:155763005-155764081 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016979
protein coding gene Chr1:138537915-138538991 (-)
PWK/PhJ MGP_PWKPhJ_G0015674
protein coding gene Chr1:132811194-132812270 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015461
protein coding gene Chr1:137530488-137531564 (-)
WSB/EiJ MGP_WSBEiJ_G0015951
protein coding gene Chr1:138582348-138583424 (-)



Homology
more
  • Human Ortholog
    GPR25, G protein-coupled receptor 25
  • Vertebrate Orthologs
    7
  • Human Ortholog
    GPR25, G protein-coupled receptor 25
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 2848
    neXtProt AC: NX_O00155
    UniProt: O00155

  • Chr Location
    1q32.1; chr1:200872955-200874178 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Genomic Mutations
    3 involving Gpr25
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000052759 Ensembl Gene Model | MGI Sequence Detail 1077 C57BL/6J ±  kb
transcript ENSMUST00000086395 Ensembl | MGI Sequence Detail 1077 Not Applicable  
polypeptide ENSMUSP00000083583 Ensembl | MGI Sequence Detail 358 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1

    Microarray probesets 1
References
more
  • Summaries
    All 18
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:7938 Juriloff DM, et al., Genetic and developmental studies of a new mouse mutation that produces otocephaly. J Craniofac Genet Dev Biol. 1985;5(2):121-45

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory