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Mtx3 Gene Detail
Summary
  • Symbol
    Mtx3
  • Name
    metaxin 3
  • Synonyms
    4930470O13Rik, Gm6514, LOC382793
  • Feature Type
    protein coding gene
  • IDs
    MGI:2686040
    NCBI Gene: 382793
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:92844760-92858230 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 47.78 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    80 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2686040
protein coding gene Chr13:92844743-92858230 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020821
protein coding gene Chr13:94172476-94185919 (+)
A/J MGP_AJ_G0020775
protein coding gene Chr13:90674227-90687664 (+)
AKR/J MGP_AKRJ_G0020748
protein coding gene Chr13:93415911-93429354 (+)
BALB/cJ MGP_BALBcJ_G0020771
protein coding gene Chr13:91316885-91330328 (+)
C3H/HeJ MGP_C3HHeJ_G0020565
protein coding gene Chr13:93128675-93142118 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021208
protein coding gene Chr13:97038366-97051809 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018775
protein coding gene Chr13:86592394-86605912 (+)
CAST/EiJ MGP_CASTEiJ_G0020084
protein coding gene Chr13:92395650-92409076 (+)
CBA/J MGP_CBAJ_G0020524
protein coding gene Chr13:100862727-100876170 (+)
DBA/2J MGP_DBA2J_G0020649
protein coding gene Chr13:90437724-90451167 (+)
FVB/NJ MGP_FVBNJ_G0020629
protein coding gene Chr13:89251874-89265313 (+)
LP/J MGP_LPJ_G0020722
protein coding gene Chr13:94290306-94303749 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020658
protein coding gene Chr13:101368283-101381726 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021248
protein coding gene Chr13:92821084-92834527 (+)
PWK/PhJ MGP_PWKPhJ_G0019836
protein coding gene Chr13:89171474-89184896 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019660
protein coding gene Chr13:89092809-89106222 (+)
WSB/EiJ MGP_WSBEiJ_G0020141
protein coding gene Chr13:93308616-93322071 (+)



Homology
more
  • Human Ortholog
    MTX3, metaxin 3
  • Vertebrate Orthologs
    11
  • Human Ortholog
    MTX3, metaxin 3
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 345778
    neXtProt AC: NX_Q5HYI7
    UniProt: Q5HYI7

  • Chr Location
    5q14.1; chr5:79976716-79991267 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 46611
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MTX3
  • Protein SuperFamily
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021704 Ensembl Gene Model | MGI Sequence Detail 13471 C57BL/6J ±  kb
transcript ENSMUST00000076169 Ensembl | MGI Sequence Detail 6275 Not Applicable  
polypeptide ENSMUSP00000075526 Ensembl | MGI Sequence Detail 312 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR036282 Glutathione S-transferase, C-terminal domain superfamily
    IPR040079 Glutathione Transferase family
    IPR033468 Metaxin, glutathione S-transferase domain
    IPR017410 Mitochondrial outer membrane transport complex protein, metaxin
    IPR019564 Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 4
Other
Accession IDs
less
MGI:1922212, MGI:2145150, MGI:2145308, MGI:2145382, MGI:3647561
References
more
  • Summaries
    All 25
    Phenotypes 6
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:90607 Adolph KW, The zebrafish metaxin 3 gene (mtx3): cDNA and protein structure, and comparison to zebrafish metaxins 1 and 2. Gene. 2004 Apr 14;330:67-73

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory