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Bclaf3 Gene Detail
Summary
  • Symbol
    Bclaf3
  • Name
    Bclaf1 and Thrap3 family member 3
  • Synonyms
    2310067E24Rik, A830080D01Rik, LOC382252
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685992
    NCBI Gene: 382252
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:158315639-158376077 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 73.55 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1176 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685992
 protein coding gene ChrX:158309684-158376077 (+)
129S1/SvImJ ENSMUSG00200024255
 protein coding gene ChrX:135031471-135097869 (+)
A/J ENSMUSG00195037266
 protein coding gene ChrX:140154770-140221171 (+)
AKR/J ENSMUSG00220026631
 protein coding gene ChrX:132010843-132077240 (+)
BALB/cJ ENSMUSG00180037256
 protein coding gene ChrX:135521522-135587742 (+)
C3H/HeJ ENSMUSG00175025131
 protein coding gene ChrX:140092566-140158961 (+)
C57BL/6NJ ENSMUSG00215021234
 protein coding gene ChrX:135924814-135991216 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033533
 protein coding gene ChrX:147972377-148039178 (+)
CAST/EiJ ENSTCUG00005030166
 protein coding gene ChrX:137702889-137770352 (+)
CBA/J ENSMUSG00210033548
 protein coding gene ChrX:137415060-137481453 (+)
DBA/2J ENSMUSG00185044976
 protein coding gene ChrX:152361008-152427405 (+)
FVB/NJ ENSMUSG00205019983
 protein coding gene ChrX:136030688-136097092 (+)
JF1/MsJ ENSUMUG00000034383
 protein coding gene ChrX:172782127-172849947 (+)
LP/J ENSMUSG00230012788
 protein coding gene ChrX:159150921-159217314 (+)
NOD/ShiLtJ ENSMUSG00190030917
 protein coding gene ChrX:136500152-136566547 (+)
NZO/HlLtJ ENSMUSG00225041335
 protein coding gene ChrX:162540145-162606543 (+)
PWK/PhJ ENSLUMG00010039902
 protein coding gene ChrX:133874892-133942669 (+)
SPRET/EiJ ENSMSPG00010019012
 protein coding gene ChrX:138949029-139023489 (+)
WSB/EiJ ENSIUOG00005024892
 protein coding gene ChrX:136838582-136904798 (+)



Homology
more
  • Human Ortholog
    BCLAF3, BCLAF1 and THRAP3 family member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BCLAF3, BCLAF1 and THRAP3 family member 3
  • Synonyms
    CXorf23, TOBF1
  • Links
    NCBI Gene ID: 256643
    UniProt: A2AJT9

  • Chr Location
    Xp22.12; chrX:19912860-19991097 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 1 genetic background
    4 images
    15 phenotype references
  • All Mutations and Alleles
    80
  • Endonuclease-mediated
    3
  • Gene trapped
    73
  • Radiation induced
    1
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Bclaf3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    94 strains or lines available
Male chimeras hemizygous for either of two different gene trapped alleles of this gene appear normal at E8.5.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    626
  • Tissues
    29
  • cDNA Data
    46
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 382252 NCBI Gene Model | MGI Sequence Detail 60439 C57BL/6J ±  kb
transcript NR_152562 RefSeq | MGI Sequence Detail 4215 C57BL/6  
polypeptide A2AG58 UniProt | EBI | MGI Sequence Detail 752 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 48
    Genomic 2
    cDNA 46

    Microarray probesets 5
Other
Accession IDs
less
MGI:1916899, MGI:5906013
References
more
  • Summaries
    All 42
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 15
  • Earliest
    J:46359 Blair HJ, et al., Mouse mutants carrying deletions that remove the genes mutated in Coffin-Lowry syndrome and lactic acidosis. Hum Mol Genet. 1998 Mar;7(3):549-55
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory