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Pabpn1l Gene Detail
Summary
  • Symbol
    Pabpn1l
  • Name
    poly(A)binding protein nuclear 1-like
  • Synonyms
    ePABP2, LOC382035
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685954
    NCBI Gene: 382035
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr8:122619471-122622739 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3269 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 71.93 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    PABPN1L, poly(A) binding protein nuclear 1 like, cytoplasmic
  • Vertebrate Orthologs
    6
  • Human Ortholog
    PABPN1L, poly(A) binding protein nuclear 1 like, cytoplasmic
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ePABP2, PABPNL1
  • Links
    NCBI Gene ID: 390748
    neXtProt AC: NX_A6NDY0
    UniProt: A6NDY0

  • Chr Location
    16q24.3; chr16:88862623-88870152 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000020627 VEGA Gene Model | MGI Sequence Detail 3269 C57BL/6J ±  kb
    transcript OTTMUST00000150953 VEGA | MGI Sequence Detail 1113 Not Applicable  
    polypeptide OTTMUSP00000078289 VEGA | MGI Sequence Detail 288 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      108 from dbSNP Build 142
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • InterPro Domains
      IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
      IPR035979 RNA-binding domain superfamily
      IPR000504 RNA recognition motif domain
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 11
      Primer pair 1

      Microarray probesets 1
    References
    more
    • Summaries
      All 20
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 5
    • Earliest
      J:90578 Good PJ, et al., Xenopus embryonic poly(A) binding protein 2 (ePABP2) defines a new family of cytoplasmic poly(A) binding proteins expressed during the early stages of vertebrate development. Genesis. 2004 Apr;38(4):166-75
    • Latest
      J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    06/12/2018
    MGI 6.12
    The Jackson Laboratory