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Pabpn1l
Gene Detail
 Symbol
Name
ID
Pabpn1l
poly(A)binding protein nuclear 1-like
MGI:2685954
Synonyms ePABP2, LOC382035
Feature Type protein coding gene
Genetic Map
Chromosome 8
71.93 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr8:122619471-122622739 bp, - strand
From VEGA annotation of GRCm38

  3269 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:19736  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle

Gene Tree: Pabpn1l

Human
homologs
Human Homolog PABPN1L, poly(A) binding protein, nuclear 1-like (cytoplasmic)
NCBI Gene ID 390748
neXtProt AC  NX_A6NDY0
Human Synonyms  ePABP2, PABPNL1
Human Chr (Location)  16q24.3; chr16:88863338-88866660 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pabpn1l interacts with 48 markers (Mir24-1, Mir24-2, Mir26a-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process biological_process
Component cytoplasm
Function nucleic acid binding, nucleotide binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (14)    Tissues (12)    Images (2)
Theiler Stages: 4, 17, 28
Assay TypeResults
Northern blot 10
RT-PCR 4
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) cDNA(11) Primer pair(1)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000020627 (Evidence)
Ensembl Gene ModelENSMUSG00000069867 (Evidence)
Entrez Gene382035 (Evidence)
UniGene25449
NIA Mouse Gene IndexU030361
Consensus CDS ProjectCCDS22743.1
International Mouse Knockout Project StatusPabpn1l
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020627 VEGA Gene Model | MGI Sequence Detail 3269 C57BL/6J ±  kb
transcript OTTMUST00000048864 VEGA | MGI Sequence Detail 1148 Not Applicable 
polypeptide OTTMUSP00000022515 VEGA | MGI Sequence Detail 273 Not Applicable 

For the selected sequences
All sequences(16) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(108 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR000504 RNA recognition motif domain
Protein Ontology PR:000012211 embryonic polyadenylate-binding protein 2
References (Earliest) J:90578 Good PJ, et al., Xenopus embryonic poly(A) binding protein 2 (ePABP2) defines a new family of cytoplasmic poly(A) binding proteins expressed during the early stages of vertebrate development. Genesis. 2004 Apr;38(4):166-75
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(22)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory