About   Help   FAQ
Pabpn1l
Gene Detail
Symbol

Name
ID
Pabpn1l
poly(A)binding protein nuclear 1-like
MGI:2685954
Synonyms
ePABP2, LOC382035
Feature Type
protein coding gene
Genetic Map
Chromosome 8
71.93 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr8:122619471-122622739 bp, - strand
From VEGA annotation of GRCm38

  3269 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:19736  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle

HCOP human homology predictions: PABPN1L
Gene Tree: Pabpn1l

Human
homologs
PABPN1L, poly(A) binding protein, nuclear 1-like (cytoplasmic)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 390748
neXtProt AC: NX_A6NDY0

Human Synonyms: ePABP2, PABPNL1

Human Chr (Location): 16q24.3; chr16:88862623-88870156 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pabpn1l interacts with 48 markers (Mir24-1, Mir24-2, Mir26a-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process biological_process
Component cytoplasm
Function nucleic acid binding, nucleotide binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (14)    Tissues (12)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
Northern blot 10
RT-PCR 4
cDNA source data(11)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase pabpn1l    NEW 
Molecular
reagents
All nucleic(12) cDNA(11) Primer pair(1)
Microarray probesets(1)
Other database
links
VEGA Gene Model OTTMUSG00000020627 (Evidence)
Ensembl Gene Model ENSMUSG00000069867 (Evidence)
Entrez Gene 382035 (Evidence)
UniGene 25449
NIA Mouse Gene Index U030361
Consensus CDS Project CCDS22743.1
International Mouse Phenotyping Consortium Status Pabpn1l
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020627 VEGA Gene Model | MGI Sequence Detail 3269 C57BL/6J ±  kb
transcript OTTMUST00000048864 VEGA | MGI Sequence Detail 1148 Not Applicable 
polypeptide OTTMUSP00000022515 VEGA | MGI Sequence Detail 273 Not Applicable 

For the selected sequences
All sequences(16) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(108 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012677 Nucleotide-binding alpha-beta plait domain
InterPro IPR000504 RNA recognition motif domain
Protein Ontology PR:000012211 embryonic polyadenylate-binding protein 2
References
(Earliest) J:90578 Good PJ, et al., Xenopus embryonic poly(A) binding protein 2 (ePABP2) defines a new family of cytoplasmic poly(A) binding proteins expressed during the early stages of vertebrate development. Genesis. 2004 Apr;38(4):166-75
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(21)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/25/2015
MGI 6.0
The Jackson Laboratory