Aadacl4fm1 Gene Detail

Summary

• Symbol
  Aadacl4fm1
• Name
  AADACL4 family member 1
• Synonyms
  9430007A20Rik, LOC381572

• Feature Type
  protein coding gene
• IDs
  MGI:2685880
  NCBI Gene: 381572
• Alliance
  gene page
• Transcription Start Sites
  6 TSS

Location &
Maps

• Sequence Map
  Chr4:144246392-144255923 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 4, 77.98 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  217 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685880	protein coding gene	Chr4:144246392-144255923 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0029094	protein coding gene	Chr4:147886001-147896786 (+)
A/J	MGP_AJ_G0029061	protein coding gene	Chr4:141622188-141637934 (+)
AKR/J	MGP_AKRJ_G0029009	protein coding gene	Chr4:145585949-145595615 (+)
BALB/cJ	MGP_BALBcJ_G0029076	protein coding gene	Chr4:142260632-142270006 (+)
C3H/HeJ	MGP_C3HHeJ_G0028795	protein coding gene	Chr4:146040635-146049935 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0029521	protein coding gene	Chr4:152909183-152923078 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0026773	protein coding gene	Chr4:134312442-134320880 (+)
CAST/EiJ	MGP_CASTEiJ_G0028211	protein coding gene	Chr4:144124526-144133313 (+)
CBA/J	MGP_CBAJ_G0028759	protein coding gene	Chr4:157694427-157703649 (+)
DBA/2J	MGP_DBA2J_G0028907	protein coding gene	Chr4:141834081-141843330 (+)
FVB/NJ	MGP_FVBNJ_G0028869	protein coding gene	Chr4:140961688-140972917 (+)
LP/J	MGP_LPJ_G0028998	protein coding gene	Chr4:147955225-147966278 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0028899	protein coding gene	Chr4:161240787-161250118 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0029558	protein coding gene	Chr4:146056132-146069133 (+)
PWK/PhJ	MGP_PWKPhJ_G0027931	protein coding gene	Chr4:138315089-138324751 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0027765	protein coding gene	Chr4:141337169-141351651 (+)
WSB/EiJ	MGP_WSBEiJ_G0028290	protein coding gene	Chr4:146321099-146331008 (+)

Homology

• Human Ortholog
  AADACL4, arylacetamide deacetylase like 4

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  AADACL4, arylacetamide deacetylase like 4
  
• Links
  HGNC:32038

  NCBI Gene ID: 343066

  UniProt: Q5VUY2

  
  
• Chr Location
  1p36.21; chr1:12644085-12667076 (+)  GRCh38

---

• MGI Vertebrate Homology
  Aadacl4fm1 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: AADACL4
• Gene Tree
  Aadacl4fm1
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  4 phenotype references
  

• All Mutations and Alleles
  4
• Chemically induced (other)
  1
• Endonuclease-mediated
  2
• Targeted
  1
• Genomic Mutations
  2 involving Aadacl4fm1
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  17 strains or lines available

Gene Ontology
(GO)
Classifications

Expression

• Assay Results
  829
• Tissues
  8
• cDNA Data
  4
• Literature Summary
  1

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  28
• RefSeq
  2
• UniProt
  2
• CCDS
  CCDS51366.1

• Ensembl
  ENSMUSG00000028593 (Evidence)
• NCBI Gene
  381572

Representative Sequences			Length	Strain/Species
genomic	381572	NCBI Gene Model | MGI Sequence Detail	9532	C57BL/6J
transcript	NM_198662	RefSeq | MGI Sequence Detail	1406	C57BL/6
polypeptide	Q8BM81	UniProt | EBI | MGI Sequence Detail	407	Not Applicable

Protein
Information

• UniProt
  2 Sequences
• Protein Ontology
  PR:000003524 arylacetamide deacetylase-like 4
  (term hierarchy)
• EC
  3.1.1.-
• InterPro Domains
  IPR029058 Alpha/Beta hydrolase fold
  IPR013094 Alpha/beta hydrolase fold-3
  IPR050300 'GDXG' lipolytic enzyme
• GlyGen
  Q8BM81 1 site

Molecular
Reagents

• All nucleic 4

  cDNA 4

  
  

  Microarray probesets 2

Other
Accession IDs

MGI:6330746

References

• Summaries
  All 18

  Developmental Gene Expression 1

  Phenotypes 4
• Earliest
  J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
• Latest
  J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Aadacl4fm1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr40138	Chr4:144246384-144246405 (+)	3 bp
Tssr40139	Chr4:144246793-144246803 (+)	406 bp
Tssr40140	Chr4:144248799-144248817 (+)	2,416 bp
Tssr40141	Chr4:144250200-144250224 (+)	3,820 bp
Tssr40142	Chr4:144255795-144255802 (+)	9,407 bp
Tssr40143	Chr4:144255831-144255838 (+)	9,443 bp