Cd101 Gene Detail

Summary

• Symbol
  Cd101
• Name
  CD101 antigen
• Synonyms
  Igsf2, LOC381460

• Feature Type
  protein coding gene
• IDs
  MGI:2685862
  NCBI Gene: 630146
• Gene Overview
  MyGene.info: CD101
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr3:100993529-101029495 bp, - strand
• From NCBI annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 3, 43.90 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  337 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685862	protein coding gene	Chr3:100993529-101029556 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0027672	protein coding gene	Chr3:102135412-102176410 (-)
A/J	MGP_AJ_G0027631	protein coding gene	Chr3:98915020-98954212 (-)
AKR/J	MGP_AKRJ_G0027597	protein coding gene	Chr3:101345322-101384419 (-)
BALB/cJ	MGP_BALBcJ_G0027644	protein coding gene	Chr3:98675366-98711570 (-)
C3H/HeJ	MGP_C3HHeJ_G0027373	protein coding gene	Chr3:101637723-101674816 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0028087	protein coding gene	Chr3:105885160-105923485 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025428	protein coding gene	Chr3:95112615-95152738 (-)
CAST/EiJ	MGP_CASTEiJ_G0026829	protein coding gene	Chr3:100741248-100778653 (-)
CBA/J	MGP_CBAJ_G0027348	protein coding gene	Chr3:109530530-109572841 (-)
DBA/2J	MGP_DBA2J_G0027491	protein coding gene	Chr3:98156009-98192472 (-)
FVB/NJ	MGP_FVBNJ_G0027459	protein coding gene	Chr3:96088586-96125627 (-)
LP/J	MGP_LPJ_G0027598	protein coding gene	Chr3:103497107-103534010 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027489	protein coding gene	Chr3:115752154-115791312 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0028142	protein coding gene	Chr3:100832063-100870634 (-)
PWK/PhJ	MGP_PWKPhJ_G0026556	protein coding gene	Chr3:97912072-97949147 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0026378	protein coding gene	Chr3:98925139-98963855 (-)
WSB/EiJ	MGP_WSBEiJ_G0026909	protein coding gene	Chr3:101393066-101429107 (-)

Homology

• Human Ortholog
  CD101, CD101 molecule

• Vertebrate Orthologs
  7

• Human Ortholog
  CD101, CD101 molecule
  Orthology source: HomoloGene, HGNC
• Synonyms
  EWI-101, IGSF2, V7
• Links
  HGNC:5949

  NCBI Gene ID: 9398

  neXtProt AC: NX_Q93033

  UniProt: Q93033

  
  
• Chr Location
  1p13.1; chr1:116990423-117037481 (+)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 3142
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 macaque, rhesus
  
• HCOP
  human homology predictions: CD101
• Gene Tree
  Cd101
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  6 phenotype references
  

• All Mutations and Alleles
  6
• Chemically induced (other)
  1
• Gene trapped
  3
• Radiation induced
  1
• Targeted
  1
• Genomic Mutations
  2 involving Cd101
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  31 strains or lines available

Mice homozygous for a knock-out allele exhibit reduced Gr-1+ cells.

Gene Ontology
(GO)
Classifications

• All GO Annotations
  4
• GO References
  4

• External Resources
  FuncBase

Expression

• cDNA Data
  2

• Other Mouse Links
  GEO
  Expression Atlas

Interactions

• Cd101 interacts with 39 markers (Mir100, Mir183, Mir188, ...) View All

Sequences &
Gene Models

• All Sequences
  34
• RefSeq
  5
• UniProt
  2
• CCDS
  CCDS51019.1, CCDS51020.1
• UniGene
  190915

• Ensembl
  ENSMUSG00000086564 (Evidence)
• NCBI Gene
  630146 (Evidence)

Representative Sequences			Length	Strain/Species
genomic	630146	NCBI Gene Model | MGI Sequence Detail	35967	C57BL/6J
transcript	NM_001167906	RefSeq | MGI Sequence Detail	3254	C57BL/6
polypeptide	A8E0Y8	UniProt | EBI | MGI Sequence Detail	1033	Not Applicable

Protein
Information

• UniProt
  2 Sequences
• Protein Ontology
  PR:000001089 immunoglobulin superfamily member 2
  (term hierarchy)
• InterPro Domains
  IPR007110 Immunoglobulin-like domain
  IPR036179 Immunoglobulin-like domain superfamily
  IPR013783 Immunoglobulin-like fold
  IPR003599 Immunoglobulin subtype
  IPR003598 Immunoglobulin subtype 2
  IPR013106 Immunoglobulin V-set domain

Molecular
Reagents

• All nucleic 2

  cDNA 2

  
  

  Microarray probesets 1

Other
Accession IDs

MGI:2685580

References

• Summaries
  All 26

  Diseases 1

  Gene Ontology 4

  Phenotypes 6
• Earliest
  J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
• Latest
  J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

TSS for Cd101:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr34768	Chr3:101029543-101029558 (-)	-56 bp
Tssr34767	Chr3:101029524-101029533 (-)	-34 bp