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Gpr176 Gene Detail
Summary
  • Symbol
    Gpr176
  • Name
    G protein-coupled receptor 176
  • Synonyms
    LOC381413
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685858
    NCBI Gene: 381413
  • Gene Overview
    MyGene.info: GPR176
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:118277110-118373419 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 59.40 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1038 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685858
protein coding gene Chr2:118277096-118374549 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026313
protein coding gene Chr2:120956166-121058356 (-)
A/J MGP_AJ_G0026274
protein coding gene Chr2:116044588-116141467 (-)
AKR/J MGP_AKRJ_G0026253
protein coding gene Chr2:119304507-119403531 (-)
BALB/cJ MGP_BALBcJ_G0026287
protein coding gene Chr2:116301072-116397426 (-)
C3H/HeJ MGP_C3HHeJ_G0026033
protein coding gene Chr2:119756342-119851914 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026734
protein coding gene Chr2:124952925-125056382 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024114
protein coding gene Chr2:111091471-111184589 (-)
CAST/EiJ MGP_CASTEiJ_G0025495
protein coding gene Chr2:120060434-120162224 (-)
CBA/J MGP_CBAJ_G0026009
protein coding gene Chr2:129368623-129474830 (-)
DBA/2J MGP_DBA2J_G0026148
protein coding gene Chr2:115467480-115562780 (-)
FVB/NJ MGP_FVBNJ_G0026110
protein coding gene Chr2:114295715-114390894 (-)
LP/J MGP_LPJ_G0026249
protein coding gene Chr2:121275861-121376632 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026129
protein coding gene Chr2:133748453-133853783 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026789
protein coding gene Chr2:119417565-119516856 (-)
PWK/PhJ MGP_PWKPhJ_G0025231
protein coding gene Chr2:115017003-115115062 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025030
protein coding gene Chr2:118587228-118686071 (-)
WSB/EiJ MGP_WSBEiJ_G0025564
protein coding gene Chr2:120239499-120340390 (-)



Homology
more
  • Human Ortholog
    GPR176, G protein-coupled receptor 176
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GPR176, G protein-coupled receptor 176
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HB-954
  • Links
    NCBI Gene ID: 11245
    neXtProt AC: NX_Q14439
    UniProt: Q14439

  • Chr Location
    15q14-q15.1; chr15:39795049-39920933 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit shortened circadian period.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000040133 Ensembl Gene Model | MGI Sequence Detail 96310 C57BL/6J ±  kb
    transcript ENSMUST00000039160 Ensembl | MGI Sequence Detail 3899 Not Applicable  
    polypeptide ENSMUSP00000037586 Ensembl | MGI Sequence Detail 515 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 11

      Microarray probesets 3
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 11
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:291611 Wang T, et al., Identification and functional characterisation of N-linked glycosylation of the orphan G protein-coupled receptor Gpr176. Sci Rep. 2020 Mar 10;10(1):4429

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    10/13/2020
    MGI 6.16
    The Jackson Laboratory