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Zfp408 Gene Detail
Summary
  • Symbol
    Zfp408
  • Name
    zinc finger protein 408
  • Synonyms
    LOC381410
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685857
    NCBI Gene: 381410
  • Gene Overview
    MyGene.info: ZNF408
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:91643669-91649791 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 50.63 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    52 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685857
protein coding gene Chr2:91642756-91649875 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026153
protein coding gene Chr2:92993211-92999375 (-)
A/J MGP_AJ_G0026114
protein coding gene Chr2:89263278-89269408 (-)
AKR/J MGP_AKRJ_G0026095
protein coding gene Chr2:91731796-91737840 (-)
BALB/cJ MGP_BALBcJ_G0026123
protein coding gene Chr2:89447284-89453376 (-)
C3H/HeJ MGP_C3HHeJ_G0025874
protein coding gene Chr2:92014293-92020355 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026574
protein coding gene Chr2:96245973-96252098 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023965
protein coding gene Chr2:85760870-85766923 (-)
CAST/EiJ MGP_CASTEiJ_G0025339
protein coding gene Chr2:92561941-92569468 (-)
CBA/J MGP_CBAJ_G0025852
protein coding gene Chr2:99550010-99556123 (-)
DBA/2J MGP_DBA2J_G0025988
protein coding gene Chr2:88866194-88872074 (-)
FVB/NJ MGP_FVBNJ_G0025951
protein coding gene Chr2:87964944-87970845 (-)
LP/J MGP_LPJ_G0026092
protein coding gene Chr2:93210562-93216696 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025977
protein coding gene Chr2:102568964-102575141 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026628
protein coding gene Chr2:91805186-91811322 (-)
PWK/PhJ MGP_PWKPhJ_G0025074
protein coding gene Chr2:88598216-88604325 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024875
protein coding gene Chr2:91387419-91392307 (-)
WSB/EiJ MGP_WSBEiJ_G0025406
protein coding gene Chr2:92405228-92411364 (-)



Homology
more
  • Human Ortholog
    ZNF408, zinc finger protein 408
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ZNF408, zinc finger protein 408
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EVR6, RP72
  • Links
    NCBI Gene ID: 79797
    neXtProt AC: NX_Q9H9D4
    UniProt: Q9H9D4

  • Chr Location
    11p11.2; chr11:46700767-46705916 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human ZNF408 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000075040 Ensembl Gene Model | MGI Sequence Detail 6123 C57BL/6J ±  kb
transcript ENSMUST00000099714 Ensembl | MGI Sequence Detail 3469 Not Applicable  
polypeptide ENSMUSP00000097301 Ensembl | MGI Sequence Detail 710 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR036236 Zinc finger C2H2 superfamily
    IPR013087 Zinc finger C2H2-type
Molecular
Reagents
less
  • All nucleic 22
    cDNA 21
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 30
    Gene Ontology 1
    Phenotypes 15
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory