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Zfp408 Gene Detail
Summary
  • Symbol
    Zfp408
  • Name
    zinc finger protein 408
  • Synonyms
    LOC381410
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685857
    NCBI Gene: 381410
  • Gene Overview
    MyGene.info: ZNF408
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr2:91643669-91649791 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6123 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 50.63 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ZNF408, zinc finger protein 408
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ZNF408, zinc finger protein 408
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EVR6, RP72
  • Links
    NCBI Gene ID: 79797
    neXtProt AC: NX_Q9H9D4
    UniProt: Q9H9D4

  • Chr Location
    11p11.2; chr11:46700767-46705916 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human ZNF408 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014301 VEGA Gene Model | MGI Sequence Detail 6123 C57BL/6J ±  kb
transcript OTTMUST00000033706 VEGA | MGI Sequence Detail 3469 Not Applicable  
polypeptide OTTMUSP00000015107 VEGA | MGI Sequence Detail 710 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    52 from dbSNP Build 142
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR009017 Green fluorescent protein
    IPR036236 Zinc finger C2H2 superfamily
    IPR013087 Zinc finger C2H2-type
    IPR013083 Zinc finger, RING/FYVE/PHD-type
Molecular
Reagents
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  • All nucleic 21
    cDNA 20
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 30
    Gene Ontology 1
    Phenotypes 15
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory