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Bpifb4 Gene Detail
Summary
  • Symbol
    Bpifb4
  • Name
    BPI fold containing family B, member 4
  • Synonyms
    Gm1006, LOC381399
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685852
    NCBI Gene: 381399
  • Gene Overview
    MyGene.info: BPIFB4
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:153938217-153963852 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 75.99 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    605 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685852
protein coding gene Chr2:153938212-153964101 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026703
protein coding gene Chr2:158647441-158674758 (+)
A/J MGP_AJ_G0026669
protein coding gene Chr2:152259245-152285742 (+)
AKR/J MGP_AKRJ_G0026640
protein coding gene Chr2:156743424-156769544 (+)
BALB/cJ MGP_BALBcJ_G0026679
protein coding gene Chr2:152596670-152623502 (+)
C3H/HeJ MGP_C3HHeJ_G0026421
protein coding gene Chr2:157114486-157140501 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027128
protein coding gene Chr2:163272742-163298631 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024498
protein coding gene Chr2:145832749-145859679 (+)
CAST/EiJ MGP_CASTEiJ_G0025882
protein coding gene Chr2:157382964-157409222 (+)
CBA/J MGP_CBAJ_G0026400
protein coding gene Chr2:169270944-169298838 (+)
DBA/2J MGP_DBA2J_G0026535
protein coding gene Chr2:151486018-151512525 (+)
FVB/NJ MGP_FVBNJ_G0026501
protein coding gene Chr2:149933736-149960578 (+)
LP/J MGP_LPJ_G0026640
protein coding gene Chr2:158766160-158792016 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026523
protein coding gene Chr2:173252361-173279628 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027183
protein coding gene Chr2:156629179-156655068 (+)
PWK/PhJ MGP_PWKPhJ_G0025616
protein coding gene Chr2:151015546-151044089 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025419
protein coding gene Chr2:155486104-155515557 (+)
WSB/EiJ MGP_WSBEiJ_G0025952
protein coding gene Chr2:157537861-157564879 (+)



Homology
more
  • Human Ortholog
    BPIFB4, BPI fold containing family B member 4
  • Vertebrate Orthologs
    7
  • Human Ortholog
    BPIFB4, BPI fold containing family B member 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C20orf186, dJ726C3.5, LPLUNC4, RY2G5
  • Links
    NCBI Gene ID: 149954
    neXtProt AC: NX_P59827
    UniProt: P59827

  • Chr Location
    20q11.21; chr20:33081512-33111751 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 381399 NCBI Gene Model | MGI Sequence Detail 25636 C57BL/6J ±  kb
transcript NM_001034875 RefSeq | MGI Sequence Detail 2115 C57BL/6  
polypeptide A2BGH0 UniProt | EBI | MGI Sequence Detail 617 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000009900 BPI fold-containing family B member 4
  • InterPro Domains
    IPR017943 Bactericidal permeability-increasing protein, alpha/beta domain superfamily
    IPR032942 BPI/LBP/Plunc family
    IPR001124 Lipid-binding serum glycoprotein, C-terminal
    IPR017942 Lipid-binding serum glycoprotein, N-terminal
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 1
References
more
  • Summaries
    All 21
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:89705 Bingle CD, et al., Phylogenetic and evolutionary analysis of the PLUNC gene family. Protein Sci. 2004 Feb;13(2):422-30
  • Latest
    J:174122 Bingle CD, et al., Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily. Biochem Soc Trans. 2011 Aug 1;39(4):977-83

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory