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Dnah7a Gene Detail
Summary
  • Symbol
    Dnah7a
  • Name
    dynein, axonemal, heavy chain 7A
  • Synonyms
    Dnahc7, Dnahc7a, LOC381341
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685838
    NCBI Gene: 627872
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:53397006-53706784 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 26.99 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1545 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685838
protein coding gene Chr1:53396995-53708118 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015998
protein coding gene Chr1:45666245-45699092 (+)
A/J MGP_AJ_G0016004
protein coding gene Chr1:51484949-51493640 (-)
AKR/J MGP_AKRJ_G0015960
protein coding gene Chr1:52840104-52854980 (-)
BALB/cJ MGP_BALBcJ_G0015937
protein coding gene Chr1:43409109-43412916 (+)
C3H/HeJ MGP_C3HHeJ_G0015769
protein coding gene Chr1:44804851-44833988 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016412
protein coding gene Chr1:55563354-55573889 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014112
protein coding gene Chr1:40397283-40406434 (+)
CAST/EiJ MGP_CASTEiJ_G0015350
protein coding gene Chr1:44719306-45118834 (+)
CBA/J MGP_CBAJ_G0015763
protein coding gene Chr1:57111115-57122754 (-)
DBA/2J MGP_DBA2J_G0015842
protein coding gene Chr1:43066570-43069941 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0015936
protein coding gene Chr1:54147516-54157323 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0016436
protein coding gene Chr1:44610906-44617658 (+)
PWK/PhJ MGP_PWKPhJ_G0015134
protein coding gene Chr1:42926606-42933540 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014940
protein coding gene Chr1:52234955-52237205 (-)
WSB/EiJ MGP_WSBEiJ_G0015412
protein coding gene Chr1:44576665-45004039 (+)



Homology
more
  • Human Ortholog
    DNAH7, dynein axonemal heavy chain 7
  • Vertebrate Orthologs
    12
  • Human Ortholog
    DNAH7, dynein axonemal heavy chain 7
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 56171
    neXtProt AC: NX_Q8WXX0
    UniProt: Q8WXX0

  • Chr Location
    2q32.3; chr2:195737604-196075188 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41287
    1 human;3 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DNAH7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000096141 Ensembl Gene Model | MGI Sequence Detail 309779 C57BL/6J ±  kb
transcript ENSMUST00000094964 Ensembl | MGI Sequence Detail 12245 Not Applicable  
polypeptide ENSMUSP00000092571 Ensembl | MGI Sequence Detail 4024 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR026983 Dynein heavy chain
    IPR024317 Dynein heavy chain, AAA module D4
    IPR035706 Dynein heavy chain, ATP-binding dynein motor region D5
    IPR024743 Dynein heavy chain, coiled coil stalk
    IPR004273 Dynein heavy chain domain
    IPR013602 Dynein heavy chain, domain-2
    IPR035699 Dynein heavy chain, hydrolytic ATP-binding dynein motor region D1
    IPR018247 EF-Hand 1, calcium-binding site
    IPR002048 EF-hand domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
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  • All nucleic 4
    cDNA 4

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:208266 Dong F, et al., Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm. J Cell Biol. 2014 Jan 20;204(2):203-13

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory