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Garem Gene Detail
Summary
  • Symbol
    Garem
  • Name
    GRB2 associated, regulator of MAPK1
  • Synonyms
    Fam59a, LOC381126
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685790
    NCBI Gene: 381126
Location & Maps
more
  • Sequence Map
    Chr18:21127342-21300139 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      172798 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 11.87 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    GAREM1, GRB2 associated regulator of MAPK1 subtype 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GAREM1, GRB2 associated regulator of MAPK1 subtype 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C18orf11, FAM59A, GAREM, Gm944
  • Links
    NCBI Gene ID: 64762
    neXtProt AC: NX_Q9H706

  • Chr Location
    18q12.1; chr18:32263521-32470496 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    4
  • Gene trapped
    2
  • Targeted
    2
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 381126 NCBI Gene Model | MGI Sequence Detail 172798 C57BL/6J ±  kb
transcript NM_001033445 RefSeq | MGI Sequence Detail 4783 C57BL/6  
polypeptide Q3UFT3 UniProt | EBI | MGI Sequence Detail 876 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1331 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000030427 GRB2-associated and regulator of MAPK protein 1
  • InterPro Domains
    IPR025946 CABIT domain
    IPR013761 Sterile alpha motif/pointed domain
Molecular
Reagents
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  • All nucleic 27
    cDNA 27

    Microarray probesets 4
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory