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Prickle4 Gene Detail
Summary
  • Symbol
    Prickle4
  • Name
    prickle planar cell polarity protein 4
  • Synonyms
    LOC381104
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685785
    NCBI Gene: 381104
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:47999442-48005661 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 23.87 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    162 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685785
 protein coding gene Chr17:47999399-48005834 (-)
129S1/SvImJ ENSMUSG00200027652
 protein coding gene Chr17:43203199-43207145 (-)
A/J ENSMUSG00195021184
 protein coding gene Chr17:44702889-44706837 (-)
AKR/J ENSMUSG00220034285
 protein coding gene Chr17:43702899-43706846 (-)
BALB/cJ ENSMUSG00180021151
 protein coding gene Chr17:44459235-44463183 (-)
C3H/HeJ ENSMUSG00175015473
 protein coding gene Chr17:43766822-43770770 (-)
C57BL/6NJ ENSMUSG00215018909
 protein coding gene Chr17:43322985-43326936 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021709
 protein coding gene Chr17:44398010-44404232 (-)
CAST/EiJ ENSTCUG00005023070
 protein coding gene Chr17:44476212-44480161 (-)
CBA/J ENSMUSG00210029441
 protein coding gene Chr17:43516437-43520384 (-)
DBA/2J ENSMUSG00185029316
 protein coding gene Chr17:46415421-46419370 (-)
FVB/NJ ENSMUSG00205026724
 protein coding gene Chr17:44020046-44023991 (-)
JF1/MsJ ENSUMUG00000015490
 protein coding gene Chr17:46051280-46055242 (-)
LP/J ENSMUSG00230037971
 protein coding gene Chr17:47314758-47318704 (-)
NOD/ShiLtJ ENSMUSG00190017466
 protein coding gene Chr17:43410991-43414936 (-)
NZO/HlLtJ ENSMUSG00225042081
 protein coding gene Chr17:49568103-49572049 (-)
PWK/PhJ ENSLUMG00010035162
 protein coding gene Chr17:43275005-43278969 (-)
SPRET/EiJ ENSMSPG00010029306
 protein coding gene Chr17:43475023-43481824 (-)
WSB/EiJ ENSIUOG00005024128
 protein coding gene Chr17:44368574-44372519 (-)



Homology
more
  • Human Ortholog
    PRICKLE4, prickle planar cell polarity protein 4
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRICKLE4, prickle planar cell polarity protein 4
  • Synonyms
    C6orf49, OBTP, OEBT
  • Links
    NCBI Gene ID: 29964
    UniProt: Q2TBC4

  • Chr Location
    6p21.1; chr6:41780739-41787452 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    598
  • Tissues
    1
  • cDNA Data
    4
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000096549 Ensembl Gene Model | MGI Sequence Detail 6220 C57BL/6J ±  kb
transcript ENSMUST00000113300 Ensembl | MGI Sequence Detail 1110 Not Applicable  
polypeptide ENSMUSP00000108925 Ensembl | MGI Sequence Detail 369 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
Molecular
Reagents
less
  • All nucleic 6
    cDNA 4
    Primer pair 1
    Other 1

    Microarray probesets 1
References
more
  • Summaries
    All 18
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:162220 Magdaleno S, et al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
  • Latest
    J:298302 Ru J, et al., Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis. Invest Ophthalmol Vis Sci. 2020 Nov 2;61(13):6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory