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Fam186a Gene Detail
Summary
  • Symbol
    Fam186a
  • Name
    family with sequence similarity 186, member A
  • Synonyms
    1700030F18Rik, LOC380973
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685766
    NCBI Gene: 72277
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:99816229-99864942 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 56.13 cM, cytoband F3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1182 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685766
 protein coding gene Chr15:99816226-99864974 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022345
 protein coding gene Chr15:101816039-101867919 (-)
A/J MGP_AJ_G0022303
 protein coding gene Chr15:97754332-97807327 (-)
AKR/J MGP_AKRJ_G0022279
 protein coding gene Chr15:100756910-100807725 (-)
BALB/cJ MGP_BALBcJ_G0022309
 protein coding gene Chr15:97923256-97972563 (-)
C3H/HeJ MGP_C3HHeJ_G0022077
 protein coding gene Chr15:100822076-100877964 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022754
 protein coding gene Chr15:105605797-105657583 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020280
 protein coding gene Chr15:93621381-93633742 (-)
CAST/EiJ MGP_CASTEiJ_G0021601
 protein coding gene Chr15:101687535-101736904 (-)
CBA/J MGP_CBAJ_G0022046
 protein coding gene Chr15:109209731-109268096 (-)
DBA/2J MGP_DBA2J_G0022173
 protein coding gene Chr15:97180112-97193815 (-)
FVB/NJ MGP_FVBNJ_G0022153
 protein coding gene Chr15:96176878-96224315 (-)
LP/J MGP_LPJ_G0022244
 protein coding gene Chr15:101953173-102005416 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022173
 protein coding gene Chr15:113078044-113137816 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022769
 protein coding gene Chr15:100873589-100886829 (-)
PWK/PhJ MGP_PWKPhJ_G0021340
 protein coding gene Chr15:97324089-97374758 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021175
 protein coding gene Chr15:100710623-100764888 (-)
WSB/EiJ MGP_WSBEiJ_G0021652
 protein coding gene Chr15:101394519-101446920 (-)



Homology
more
  • Human Ortholog
    FAM186A, family with sequence similarity 186 member A
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM186A, family with sequence similarity 186 member A
  • Links
    NCBI Gene ID: 121006
    UniProt: A6NE01

  • Chr Location
    12q13.12; chr12:50326230-50396622 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    24 phenotype references
  • All Mutations and Alleles
    22
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    18
  • Radiation induced
    2
  • Genomic Mutations
    3 involving Fam186a
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    100 strains or lines available
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045350 Ensembl Gene Model | MGI Sequence Detail 48714 C57BL/6J ±  kb
transcript ENSMUST00000100209 Ensembl | MGI Sequence Detail 9320 Not Applicable  
polypeptide ENSMUSP00000097783 Ensembl | MGI Sequence Detail 3035 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 4
Other
Accession IDs
less
MGI:1919527
References
more
  • Summaries
    All 45
    Diseases 1
    Phenotypes 24
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory