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Siah3 Gene Detail
Summary
  • Symbol
    Siah3
  • Name
    seven in absentia homolog 3 (Drosophila)
  • Synonyms
    LOC380918
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685758
    NCBI Gene: 380918
Location & Maps
more
  • Sequence Map
    Chr14:75455982-75526141 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      70160 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 40.08 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    SIAH3, siah E3 ubiquitin protein ligase family member 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SIAH3, siah E3 ubiquitin protein ligase family member 3
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 283514
    neXtProt AC: NX_Q8IW03

  • Chr Location
    13q14.13; chr13:45780270-45851711 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Genomic Mutations
    1 involving Siah3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 380918 NCBI Gene Model | MGI Sequence Detail 70160 C57BL/6J ±  kb
transcript NM_001128093 RefSeq | MGI Sequence Detail 905 Not Specified  
polypeptide NP_001121565 RefSeq | MGI Sequence Detail 268 Not Specified  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    524 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 1
References
more
  • Summaries
    All 16
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory