Tmem171 Gene Detail

Summary

• Symbol
  Tmem171
• Name
  transmembrane protein 171
• Synonyms
  LOC380863

• Feature Type
  protein coding gene
• IDs
  MGI:2685751
  NCBI Gene: 380863
• Alliance
  gene page
• Transcription Start Sites
  15 TSS

Location &
Maps

• Sequence Map
  Chr13:98822743-98831342 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 13, 52.13 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  77 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685751	protein coding gene	Chr13:98822743-98832142 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0020869	protein coding gene	Chr13:100421695-100430294 (-)
A/J	MGP_AJ_G0020823	protein coding gene	Chr13:96595316-96603934 (-)
AKR/J	MGP_AKRJ_G0020797	protein coding gene	Chr13:99539641-99548239 (-)
BALB/cJ	MGP_BALBcJ_G0020821	protein coding gene	Chr13:97301264-97309870 (-)
C3H/HeJ	MGP_C3HHeJ_G0020612	protein coding gene	Chr13:99286008-99294612 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0021255	protein coding gene	Chr13:103431789-103440388 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018824	protein coding gene	Chr13:92326947-92334536 (-)
CAST/EiJ	MGP_CASTEiJ_G0020130	protein coding gene	Chr13:98644679-98653291 (-)
CBA/J	MGP_CBAJ_G0020572	protein coding gene	Chr13:107540337-107551326 (-)
DBA/2J	MGP_DBA2J_G0020697	protein coding gene	Chr13:96359308-96367919 (-)
FVB/NJ	MGP_FVBNJ_G0020678	protein coding gene	Chr13:95108544-95117140 (-)
LP/J	MGP_LPJ_G0020772	protein coding gene	Chr13:100528203-100536802 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020706	protein coding gene	Chr13:107869170-107877773 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021296	protein coding gene	Chr13:98988608-98997219 (-)
PWK/PhJ	MGP_PWKPhJ_G0019883	protein coding gene	Chr13:95165699-95174364 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0019706	protein coding gene	Chr13:95273884-95282526 (-)
WSB/EiJ	MGP_WSBEiJ_G0020188	protein coding gene	Chr13:99434904-99444700 (-)

Homology

• Human Ortholog
  TMEM171, transmembrane protein 171

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  TMEM171, transmembrane protein 171
  
• Synonyms
  PRP2
• Links
  HGNC:27031

  NCBI Gene ID: 134285

  neXtProt AC: NX_Q8WVE6

  UniProt: Q8WVE6

  
  
• Chr Location
  5q13.2; chr5:73120561-73131817 (+)  GRCh38.p7

---

• Alliance of Genome Resources
  Tmem171 stringent orthology
  1 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: TMEM171
• Gene Tree
  Tmem171
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  4 phenotype references
  

• All Mutations and Alleles
  4
• Endonuclease-mediated
  2
• Targeted
  2
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  16 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  1

Expression

• Assay Results
  672
• cDNA Data
  11

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase tmem171

Interactions

• Tmem171 interacts with 18 markers (Mir7-1, Mir10a, Mir224, ...) View All

Sequences &
Gene Models

• All Sequences
  39
• RefSeq
  10
• UniProt
  2
• CCDS
  CCDS26716.1

• Ensembl
  ENSMUSG00000052485 (Evidence)
• NCBI Gene
  380863

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000052485	Ensembl Gene Model | MGI Sequence Detail	8600	C57BL/6J
transcript	ENSMUST00000064347	Ensembl | MGI Sequence Detail	1161	Not Applicable
polypeptide	ENSMUSP00000070369	Ensembl | MGI Sequence Detail	322	Not Applicable

Protein
Information

• UniProt
  2 Sequences
• Protein Ontology
  PR:000031183 transmembrane protein 171
  (term hierarchy)
• InterPro Domains
  IPR029173 Transmembrane protein family 171

Molecular
Reagents

• All nucleic 11

  cDNA 11

  
  

  Microarray probesets 3

References

• Summaries
  All 22

  Gene Ontology 1

  Phenotypes 4
• Earliest
  J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
• Latest
  J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

TSS for Tmem171:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr123645	Chr13:98832192-98832200 (-)	-854 bp
Tssr123644	Chr13:98832068-98832086 (-)	-735 bp
Tssr123643	Chr13:98831532-98831546 (-)	-197 bp
Tssr123642	Chr13:98831401-98831413 (-)	-65 bp
Tssr123641	Chr13:98831333-98831355 (-)	-2 bp
Tssr123640	Chr13:98831314-98831327 (-)	21 bp
Tssr123639	Chr13:98831277-98831304 (-)	51 bp
Tssr123638	Chr13:98829627-98829653 (-)	1,702 bp
Tssr123637	Chr13:98829297-98829315 (-)	2,036 bp
Tssr123636	Chr13:98829267-98829295 (-)	2,061 bp
Tssr123635	Chr13:98829233-98829242 (-)	2,104 bp
Tssr123634	Chr13:98829223-98829233 (-)	2,114 bp
Tssr123633	Chr13:98828703-98828725 (-)	2,628 bp
Tssr123632	Chr13:98828659-98828693 (-)	2,666 bp
Tssr123631	Chr13:98824960-98824988 (-)	6,368 bp