About   Help   FAQ
Mrs2 Gene Detail
Summary
  • Symbol
    Mrs2
  • Name
    MRS2 magnesium transporter
  • Synonyms
    LOC380836, Mrs2l
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685748
    NCBI Gene: 380836
  • Gene Overview
    MyGene.info: MRS2
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:24987483-25020365 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 10.83 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    306 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685748
protein coding gene Chr13:24987483-25020379 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020386
protein coding gene Chr13:22498114-22517683 (-)
A/J MGP_AJ_G0020335
protein coding gene Chr13:22080616-22103361 (-)
AKR/J MGP_AKRJ_G0020315
protein coding gene Chr13:22328990-22354198 (-)
BALB/cJ MGP_BALBcJ_G0020333
protein coding gene Chr13:22068205-22090998 (-)
C3H/HeJ MGP_C3HHeJ_G0020137
protein coding gene Chr13:22403653-22424478 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020770
protein coding gene Chr13:23294400-23321573 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018358
protein coding gene Chr13:20798222-20818394 (-)
CAST/EiJ MGP_CASTEiJ_G0019654
protein coding gene Chr13:22126674-22146321 (-)
CBA/J MGP_CBAJ_G0020091
protein coding gene Chr13:24183443-24214479 (-)
DBA/2J MGP_DBA2J_G0020217
protein coding gene Chr13:21573353-21606673 (-)
FVB/NJ MGP_FVBNJ_G0020201
protein coding gene Chr13:21224235-21252135 (-)
LP/J MGP_LPJ_G0020290
protein coding gene Chr13:22790762-22818219 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020228
protein coding gene Chr13:24436825-24458303 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020812
protein coding gene Chr13:22185933-22209253 (-)
PWK/PhJ MGP_PWKPhJ_G0019408
protein coding gene Chr13:21598910-21619258 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019224
protein coding gene Chr13:20960533-21036132 (-)
WSB/EiJ MGP_WSBEiJ_G0019714
protein coding gene Chr13:22342891-22362685 (-)



Homology
more
  • Human Ortholog
    MRS2, magnesium transporter MRS2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MRS2, magnesium transporter MRS2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HPT, MRS2L
  • Links
    NCBI Gene ID: 57380
    neXtProt AC: NX_Q9HD23
    UniProt: Q9HD23

  • Chr Location
    6p22.3; chr6:24402908-24426194 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 31983
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MRS2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 380836 NCBI Gene Model | MGI Sequence Detail 32883 C57BL/6J ±  kb
transcript NM_001013389 RefSeq | MGI Sequence Detail 2161 C57BL/6  
polypeptide Q5NCE8 UniProt | EBI | MGI Sequence Detail 434 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    cDNA 27

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory