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Lsmem1 Gene Detail
Summary
  • Symbol
    Lsmem1
  • Name
    leucine-rich single-pass membrane protein 1
  • Synonyms
    Gm889, LOC380755
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685735
    NCBI Gene: 380755
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:40176386-40199315 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 18.06 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    79 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685735
protein coding gene Chr12:40175493-40199490 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019701
protein coding gene Chr12:38590367-38611891 (-)
A/J MGP_AJ_G0019667
protein coding gene Chr12:37323251-37345503 (-)
AKR/J MGP_AKRJ_G0019638
protein coding gene Chr12:38450394-38473522 (-)
BALB/cJ MGP_BALBcJ_G0019645
protein coding gene Chr12:37540074-37560187 (-)
C3H/HeJ MGP_C3HHeJ_G0019449
protein coding gene Chr12:38388818-38410960 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020092
protein coding gene Chr12:39752449-39776270 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017717
protein coding gene Chr12:36461042-36476169 (-)
CAST/EiJ MGP_CASTEiJ_G0019002
protein coding gene Chr12:33575751-33596573 (-)
CBA/J MGP_CBAJ_G0019421
protein coding gene Chr12:41095753-41128564 (-)
DBA/2J MGP_DBA2J_G0019534
protein coding gene Chr12:37184720-37202434 (-)
FVB/NJ MGP_FVBNJ_G0019523
protein coding gene Chr12:36816656-36832456 (-)
LP/J MGP_LPJ_G0019604
protein coding gene Chr12:38575857-38595890 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019559
protein coding gene Chr12:41254379-41284159 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020132
protein coding gene Chr12:38012075-38032654 (-)
PWK/PhJ MGP_PWKPhJ_G0018769
protein coding gene Chr12:31862419-31879960 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018559
protein coding gene Chr12:32666018-32687210 (-)
WSB/EiJ MGP_WSBEiJ_G0019052
protein coding gene Chr12:38322449-38340348 (-)



Homology
more
  • Human Ortholog
    LSMEM1, leucine rich single-pass membrane protein 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    LSMEM1, leucine rich single-pass membrane protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C7orf53
  • Links
    NCBI Gene ID: 286006
    neXtProt AC: NX_Q8N8F7
    UniProt: Q8N8F7

  • Chr Location
    7q31.1; chr7:112480219-112491062 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 380755 NCBI Gene Model | MGI Sequence Detail 22930 C57BL/6J ±  kb
transcript NM_001033437 RefSeq | MGI Sequence Detail 1213 C57BL/6  
polypeptide Q3UQS2 UniProt | EBI | MGI Sequence Detail 128 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR028099 Protein of unknown function DUF4577
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 18
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/11/2019
MGI 6.14
The Jackson Laboratory