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Milr1 Gene Detail
Summary
  • Symbol
    Milr1
  • Name
    mast cell immunoglobulin like receptor 1
  • Synonyms
    Allergin-1, Gm885, LOC380732
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685731
    NCBI Gene: 380732
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:106642052-106659620 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 70.00 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1043 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685731
 protein coding gene Chr11:106641472-106659620 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019311
 protein coding gene Chr11:110084551-110102978 (+)
A/J MGP_AJ_G0019279
 protein coding gene Chr11:105383240-105400840 (+)
AKR/J MGP_AKRJ_G0019248
 protein coding gene Chr11:108521883-108541173 (+)
BALB/cJ MGP_BALBcJ_G0019253
 protein coding gene Chr11:105798180-105815916 (+)
C3H/HeJ MGP_C3HHeJ_G0019062
 protein coding gene Chr11:108819520-108838090 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019703
 protein coding gene Chr11:113483225-113502772 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017327
 protein coding gene Chr11:102651298-102669520 (+)
CAST/EiJ MGP_CASTEiJ_G0018615
 protein coding gene Chr11:109904582-109923385 (+)
CBA/J MGP_CBAJ_G0019031
 protein coding gene Chr11:118186698-118207627 (+)
DBA/2J MGP_DBA2J_G0019143
 protein coding gene Chr11:104852769-104870240 (+)
FVB/NJ MGP_FVBNJ_G0019134
 protein coding gene Chr11:104366510-104383906 (+)
LP/J MGP_LPJ_G0019213
 protein coding gene Chr11:110532964-110552194 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019164
 protein coding gene Chr11:117422060-117443458 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019740
 protein coding gene Chr11:109041983-109061390 (+)
PWK/PhJ MGP_PWKPhJ_G0018380
 protein coding gene Chr11:105967080-105985551 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018171
 protein coding gene Chr11:108818647-108834829 (+)
WSB/EiJ MGP_WSBEiJ_G0018666
 protein coding gene Chr11:109014346-109035353 (+)



Homology
more
  • Human Ortholog
    MILR1, mast cell immunoglobulin like receptor 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MILR1, mast cell immunoglobulin like receptor 1
  • Synonyms
    Allergin-1, C17orf60, MCA-32, MCA32
  • Links
    NCBI Gene ID: 284021
    UniProt: Q7Z6M3

  • Chr Location
    17q23.3; chr17:64449037-64497356 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 2 genetic backgrounds
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele have decreased mast cell degranulation and an increased susceptibility to type I hypersensitivity reaction.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • cDNA Data
    16
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000040528 Ensembl Gene Model | MGI Sequence Detail 17569 C57BL/6J ±  kb
    transcript ENSMUST00000147326 Ensembl | MGI Sequence Detail 1234 Not Applicable  
    polypeptide ENSMUSP00000138742 Ensembl | MGI Sequence Detail 246 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 16

      Microarray probesets 2
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 1
      Phenotypes 15
    • Earliest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory