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Uprt Gene Detail
Summary
  • Symbol
    Uprt
  • Name
    uracil phosphoribosyltransferase
  • Synonyms
    LOC331487
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685620
    NCBI Gene: 331487
Location & Maps
more
  • Sequence Map
    ChrX:104482818-104507490 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      24673 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome X, 46.67 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    UPRT, uracil phosphoribosyltransferase homolog
  • Vertebrate Orthologs
    10
  • Human Ortholog
    UPRT, uracil phosphoribosyltransferase homolog
    Orthology source: HomoloGene
  • Synonyms
    FUR1, UPP
  • Links
    NCBI Gene ID: 139596
    neXtProt AC: NX_Q96BW1

  • Chr Location
    Xq13.3; chrX:75274059-75304897 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 25175
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: UPRT
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from multigenic genotypes
    6 phenotype references
  • All Mutations and Alleles
    7
  • Gene trapped
    1
  • Targeted
    3
  • Transgenic
    3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018108 VEGA Gene Model | MGI Sequence Detail 24673 C57BL/6J ±  kb
transcript OTTMUST00000043701 VEGA | MGI Sequence Detail 2304 Not Applicable  
polypeptide OTTMUSP00000019628 VEGA | MGI Sequence Detail 310 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    67 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000017119 uracil phosphoribosyltransferase
  • InterPro Domains
    IPR029057 Phosphoribosyltransferase-like
Molecular
Reagents
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  • All nucleic 3
    cDNA 3

    Microarray probesets 2
References
more
  • Summaries
    All 18
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory