Rubcnl Gene Detail

Summary

• Symbol
  Rubcnl
• Name
  RUN and cysteine rich domain containing beclin 1 interacting protein like
• Synonyms
  5031414D18Rik, LOC380917

• Feature Type
  protein coding gene
• IDs
  MGI:2685590
  NCBI Gene: 271221
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr14:75016027-75052532 bp, + strand
• From Ensembl annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 14, 39.53 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  302 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685590	protein coding gene	Chr14:75015878-75052537 (.)
129S1/SvImJ	MGP_129S1SvImJ_G0021565	protein coding gene	Chr14:69814761-69853172 (+)
A/J	MGP_AJ_G0021523	protein coding gene	Chr14:68263700-68301639 (+)
AKR/J	MGP_AKRJ_G0021500	protein coding gene	Chr14:70285022-70321529 (+)
BALB/cJ	MGP_BALBcJ_G0021530	protein coding gene	Chr14:68062902-68099483 (+)
C3H/HeJ	MGP_C3HHeJ_G0021307	protein coding gene	Chr14:70021298-70059394 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0021970	protein coding gene	Chr14:72879544-72918557 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0019508	protein coding gene	Chr14:65908252-65944984 (+)
CAST/EiJ	MGP_CASTEiJ_G0020824	protein coding gene	Chr14:66680485-66721738 (+)
CBA/J	MGP_CBAJ_G0021275	protein coding gene	Chr14:75208224-75250269 (+)
DBA/2J	MGP_DBA2J_G0021398	protein coding gene	Chr14:67673942-67710868 (+)
FVB/NJ	MGP_FVBNJ_G0021376	protein coding gene	Chr14:67004352-67040720 (+)
LP/J	MGP_LPJ_G0021468	protein coding gene	Chr14:70975861-71015523 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0021403	protein coding gene	Chr14:73997294-74033951 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021993	protein coding gene	Chr14:69579627-69616871 (+)
PWK/PhJ	MGP_PWKPhJ_G0020567	protein coding gene	Chr14:64411093-64445658 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0020403	protein coding gene	Chr14:65522189-65564535 (+)
WSB/EiJ	MGP_WSBEiJ_G0020877	protein coding gene	Chr14:69912773-69950712 (+)

Homology

• Human Ortholog
  RUBCNL, RUN and cysteine rich domain containing beclin 1 interacting protein like

• Vertebrate Orthologs
  7

• Human Ortholog
  RUBCNL, RUN and cysteine rich domain containing beclin 1 interacting protein like
  Orthology source: HomoloGene, HGNC
• Synonyms
  C13orf18, KIAA0226L, PACER
• Links
  HGNC:20420

  NCBI Gene ID: 80183

  neXtProt AC: NX_Q9H714

  UniProt: Q9H714

  
  
• Chr Location
  13q14.13; chr13:46342000-46390042 (-)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 57021
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken
  
• HCOP
  human homology predictions: RUBCNL
• Gene Tree
  Rubcnl
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  3
• Chemically induced (other)
  1
• Targeted
  2
• Genomic Mutations
  1 involving Rubcnl
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  2 strains or lines available

Gene Ontology
(GO)
Classifications

• External Resources
  FuncBase

Expression

• cDNA Data
  12

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase rubcnl

Interactions

• Rubcnl interacts with 106 markers (Mir7-1, Mir15a, Mir15b, ...) View All

Sequences &
Gene Models

• All Sequences
  39
• RefSeq
  8
• UniProt
  4
• CCDS
  CCDS36977.1
• UniGene
  320280

• Ensembl
  ENSMUSG00000034959 (Evidence)
• NCBI Gene
  271221

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000034959	Ensembl Gene Model | MGI Sequence Detail	36506	C57BL/6J
transcript	ENSMUST00000036072	Ensembl | MGI Sequence Detail	2651	Not Applicable
polypeptide	ENSMUSP00000045566	Ensembl | MGI Sequence Detail	675	Not Applicable

Protein
Information

• UniProt
  4 Sequences
• InterPro Domains
  IPR025258 Putative zinc-RING and/or ribbon

Molecular
Reagents

• All nucleic 12

  cDNA 12

  
  

  Microarray probesets 1

Other
Accession IDs

MGI:2685757

References

• Summaries
  All 19

  Phenotypes 5
• Earliest
  J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
• Latest
  J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

TSS for Rubcnl:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr126602	Chr14:75016014-75016023 (+)	-8 bp
Tssr126603	Chr14:75016028-75016045 (+)	10 bp
Tssr126604	Chr14:75016048-75016074 (+)	34 bp